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- W1966319369 abstract "Two new sesterterpenes, thorectandrol A (1) and B (2), were isolated from extracts of the marine sponge Thorectandra sp. The structures were determined by extensive NMR spectral data analysis. NOE correlations were used to define the relative stereochemistry of 1 and 2, while CD data were used to suggest their absolute stereochemistry. Both compounds 1 and 2 inhibited the growth of MALME-3M (melanoma) and MCF-7 (breast) cancer cell lines in the range 30−40 μg/mL. The known compound palauolol (3) was isolated as well and was also cytotoxic." @default.
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- W1966319369 date "2001-04-27" @default.
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- W1966319369 title "Thorectandrols A and B, New Cytotoxic Sesterterpenes from the Marine Sponge <i>Thorectandra</i> Species" @default.
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- W1966319369 doi "https://doi.org/10.1021/np000544e" @default.
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