FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966328207> ?p ?o ?g. }

• W1966328207 endingPage "333" @default.
• W1966328207 startingPage "321" @default.
• W1966328207 abstract "Ice-structuring proteins (ISPs) naturally occur in a range of species (including edible plants and fish) that need to protect themselves against freeze damage. ISPs have potential applications in a number of areas including cryopreservation and frozen foods manufacture. However, these materials are not currently generally available for commercial use. ISP type III HPLC 12 is of particular interest and although it is likely to be consumed naturally, its toxicological safety has not previously been assessed. This paper presents data from a set of in vitro and in vivo genotoxicity assays (bacterial mutation, chromosome aberration, mammalian cell gene mutation and rat bone marrow micronucleus) and a 3-month repeat-dose gavage study in the rat using high levels of ISP type III HPLC 12 preparation produced by recombinant baker's yeast. No evidence was seen of a genotoxic potential (using levels accepted as limit concentrations for the assays used) or notable subchronic toxicity following oral administration for 3 months in the rat at up to 580 mg ISP type III HPLC 12/kg/day, the highest dose tested (which was considered to be a NOAEL)." @default.
• W1966328207 created "2016-06-24" @default.
• W1966328207 creator A5004124022 @default.
• W1966328207 creator A5056777657 @default.
• W1966328207 creator A5066251158 @default.
• W1966328207 creator A5067629383 @default.
• W1966328207 date "2004-02-01" @default.
• W1966328207 modified "2023-10-14" @default.
• W1966328207 title "Safety evaluation of ice-structuring protein (ISP) type III HPLC 12 preparation. Lack of genotoxicity and subchronic toxicity" @default.
• W1966328207 cites W1535339880 @default.
• W1966328207 cites W1563708223 @default.
• W1966328207 cites W1982994228 @default.
• W1966328207 cites W1987034447 @default.
• W1966328207 cites W1989036380 @default.
• W1966328207 cites W1992981449 @default.
• W1966328207 cites W2012708621 @default.
• W1966328207 cites W2063385774 @default.
• W1966328207 cites W2078478844 @default.
• W1966328207 cites W2082782062 @default.
• W1966328207 cites W2092316554 @default.
• W1966328207 cites W4230453355 @default.
• W1966328207 cites W4236515284 @default.
• W1966328207 cites W4244566158 @default.
• W1966328207 cites W4247972695 @default.
• W1966328207 cites W4252693454 @default.
• W1966328207 doi "https://doi.org/10.1016/j.fct.2003.09.007" @default.
• W1966328207 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14667477" @default.
• W1966328207 hasPublicationYear "2004" @default.
• W1966328207 type Work @default.
• W1966328207 sameAs 1966328207 @default.
• W1966328207 citedByCount "14" @default.
• W1966328207 countsByYear W19663282072013 @default.
• W1966328207 countsByYear W19663282072014 @default.
• W1966328207 countsByYear W19663282072020 @default.
• W1966328207 countsByYear W19663282072022 @default.
• W1966328207 countsByYear W19663282072023 @default.
• W1966328207 crossrefType "journal-article" @default.
• W1966328207 hasAuthorship W1966328207A5004124022 @default.
• W1966328207 hasAuthorship W1966328207A5056777657 @default.
• W1966328207 hasAuthorship W1966328207A5066251158 @default.
• W1966328207 hasAuthorship W1966328207A5067629383 @default.
• W1966328207 hasConcept C104317684 @default.
• W1966328207 hasConcept C143425029 @default.
• W1966328207 hasConcept C178790620 @default.
• W1966328207 hasConcept C179998833 @default.
• W1966328207 hasConcept C185592680 @default.
• W1966328207 hasConcept C2778959862 @default.
• W1966328207 hasConcept C2780358455 @default.
• W1966328207 hasConcept C29730261 @default.
• W1966328207 hasConcept C2994296024 @default.
• W1966328207 hasConcept C30481170 @default.
• W1966328207 hasConcept C31903555 @default.
• W1966328207 hasConcept C33070731 @default.
• W1966328207 hasConcept C36681516 @default.
• W1966328207 hasConcept C43617362 @default.
• W1966328207 hasConcept C45080847 @default.
• W1966328207 hasConcept C552990157 @default.
• W1966328207 hasConcept C55493867 @default.
• W1966328207 hasConcept C86803240 @default.
• W1966328207 hasConcept C98274493 @default.
• W1966328207 hasConceptScore W1966328207C104317684 @default.
• W1966328207 hasConceptScore W1966328207C143425029 @default.
• W1966328207 hasConceptScore W1966328207C178790620 @default.
• W1966328207 hasConceptScore W1966328207C179998833 @default.
• W1966328207 hasConceptScore W1966328207C185592680 @default.
• W1966328207 hasConceptScore W1966328207C2778959862 @default.
• W1966328207 hasConceptScore W1966328207C2780358455 @default.
• W1966328207 hasConceptScore W1966328207C29730261 @default.
• W1966328207 hasConceptScore W1966328207C2994296024 @default.
• W1966328207 hasConceptScore W1966328207C30481170 @default.
• W1966328207 hasConceptScore W1966328207C31903555 @default.
• W1966328207 hasConceptScore W1966328207C33070731 @default.
• W1966328207 hasConceptScore W1966328207C36681516 @default.
• W1966328207 hasConceptScore W1966328207C43617362 @default.
• W1966328207 hasConceptScore W1966328207C45080847 @default.
• W1966328207 hasConceptScore W1966328207C552990157 @default.
• W1966328207 hasConceptScore W1966328207C55493867 @default.
• W1966328207 hasConceptScore W1966328207C86803240 @default.
• W1966328207 hasConceptScore W1966328207C98274493 @default.
• W1966328207 hasIssue "2" @default.
• W1966328207 hasLocation W19663282071 @default.
• W1966328207 hasLocation W19663282072 @default.
• W1966328207 hasOpenAccess W1966328207 @default.
• W1966328207 hasPrimaryLocation W19663282071 @default.
• W1966328207 hasRelatedWork W1888660086 @default.
• W1966328207 hasRelatedWork W2011168240 @default.
• W1966328207 hasRelatedWork W2029666744 @default.
• W1966328207 hasRelatedWork W2336873102 @default.
• W1966328207 hasRelatedWork W2351232732 @default.
• W1966328207 hasRelatedWork W2393650833 @default.
• W1966328207 hasRelatedWork W2978891345 @default.
• W1966328207 hasRelatedWork W4200424613 @default.
• W1966328207 hasRelatedWork W4295969495 @default.
• W1966328207 hasRelatedWork W2572499993 @default.
• W1966328207 hasVolume "42" @default.
• W1966328207 isParatext "false" @default.
• W1966328207 isRetracted "false" @default.
• W1966328207 magId "1966328207" @default.

• next