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- W1966339916 abstract "Abstract The effects of testosterone and of dihydrotestosteron on nucleic acid synthesis by isolated prostatic nuclei from castrate rats were compared. The incorporation of cytidine into acid-insoluble material was enhanced by dihydrotestosterone but not by testosterone. Orotic acid was not incorporated into the acid-insoluble material as readily as cytidine and no hormonal effects were observed. Dihydrotestosterone inhibited the incorporation of inorganic phosphate into ATP whereas testosterone showed little inhibition. These experiments demonstrate a direct effect of androgens on isolated nuclei and support the suggestion that dihydrotestosterone rather than testosterone is the active hormone species in prostatic nuclei." @default.
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- W1966339916 date "1969-12-01" @default.
- W1966339916 modified "2023-09-27" @default.
- W1966339916 title "Effects of dihydrotestosterone on the synthesis of nucleic acid and ATP in prostatic nuclei" @default.
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- W1966339916 doi "https://doi.org/10.1016/0006-291x(69)90227-7" @default.
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