Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966339928> ?p ?o ?g. }
- W1966339928 abstract "Using a computer-controlled polarographic oxygen electrode system, the oxygen tension profiles of two rat tumors, the 13762 mammary carcinoma and the 9L gliosarcoma, and one murine tumor, the FSall fibrosarcoma, were determined under eight different conditions. The oxygen profiles were characterized by four parameters related to tumor oxygenation and by three parameters related to tumor hypoxia. In the rat 13762 mammary carcinoma tumor median pO2 and the percent of pO2 were correlated with tumor volume under three different conditions. With these tumors the decrease in percent of pO2 readings in the tumor <5 mmHg appeared to correlate with the enhancement in therapeutic response of the rat tumors to single dose radiation therapy and of the mouse tumor to single doses of melphalan or cyclophosphamide. Both the perfluorochemical emulsion (Oxygent(tm) CA) with carbogen breathing and the polymerized bovine hemoglobin with air or carbogen breathing were effective in increasing the oxygenation of these three tumors. Pentoxifylline administration especially along with carbogen breathing increased the oxygenation of the tumors. These studies indicate that the decrease in the percent of the tumor which is most severely hypoxic may be predictive of improved therapeutic response in tumors treated with oxygen-dependent or oxygen-responsive therapies and oxygen delivery agents. © Wiley-Liss, Inc." @default.
- W1966339928 created "2016-06-24" @default.
- W1966339928 creator A5000104295 @default.
- W1966339928 creator A5009519919 @default.
- W1966339928 creator A5012766276 @default.
- W1966339928 creator A5015440359 @default.
- W1966339928 creator A5024169802 @default.
- W1966339928 creator A5040137655 @default.
- W1966339928 date "1994-01-01" @default.
- W1966339928 modified "2023-09-27" @default.
- W1966339928 title "Definition and manipulation of tumor oxygenation" @default.
- W1966339928 cites W1974385690 @default.
- W1966339928 cites W1976930853 @default.
- W1966339928 cites W1979011082 @default.
- W1966339928 cites W1983474189 @default.
- W1966339928 cites W1985528986 @default.
- W1966339928 cites W1986441241 @default.
- W1966339928 cites W2000893040 @default.
- W1966339928 cites W2001090333 @default.
- W1966339928 cites W2004258125 @default.
- W1966339928 cites W2005036528 @default.
- W1966339928 cites W2005277758 @default.
- W1966339928 cites W2008828893 @default.
- W1966339928 cites W2012023411 @default.
- W1966339928 cites W2022855908 @default.
- W1966339928 cites W2031643846 @default.
- W1966339928 cites W2041001613 @default.
- W1966339928 cites W2049088667 @default.
- W1966339928 cites W2050585519 @default.
- W1966339928 cites W2055876366 @default.
- W1966339928 cites W2058096027 @default.
- W1966339928 cites W2058188494 @default.
- W1966339928 cites W2060050304 @default.
- W1966339928 cites W2060165182 @default.
- W1966339928 cites W2062822277 @default.
- W1966339928 cites W2063279862 @default.
- W1966339928 cites W2083457286 @default.
- W1966339928 cites W2128063695 @default.
- W1966339928 cites W2158743409 @default.
- W1966339928 cites W2158770528 @default.
- W1966339928 cites W2319962899 @default.
- W1966339928 cites W2328972235 @default.
- W1966339928 cites W2330819260 @default.
- W1966339928 doi "https://doi.org/10.1002/roi.2970020203" @default.
- W1966339928 hasPublicationYear "1994" @default.
- W1966339928 type Work @default.
- W1966339928 sameAs 1966339928 @default.
- W1966339928 citedByCount "9" @default.
- W1966339928 crossrefType "journal-article" @default.
- W1966339928 hasAuthorship W1966339928A5000104295 @default.
- W1966339928 hasAuthorship W1966339928A5009519919 @default.
- W1966339928 hasAuthorship W1966339928A5012766276 @default.
- W1966339928 hasAuthorship W1966339928A5015440359 @default.
- W1966339928 hasAuthorship W1966339928A5024169802 @default.
- W1966339928 hasAuthorship W1966339928A5040137655 @default.
- W1966339928 hasConcept C126322002 @default.
- W1966339928 hasConcept C142724271 @default.
- W1966339928 hasConcept C173622453 @default.
- W1966339928 hasConcept C178790620 @default.
- W1966339928 hasConcept C185592680 @default.
- W1966339928 hasConcept C2776495794 @default.
- W1966339928 hasConcept C2779081379 @default.
- W1966339928 hasConcept C2993207723 @default.
- W1966339928 hasConcept C509974204 @default.
- W1966339928 hasConcept C540031477 @default.
- W1966339928 hasConcept C70289976 @default.
- W1966339928 hasConcept C71924100 @default.
- W1966339928 hasConcept C7836513 @default.
- W1966339928 hasConceptScore W1966339928C126322002 @default.
- W1966339928 hasConceptScore W1966339928C142724271 @default.
- W1966339928 hasConceptScore W1966339928C173622453 @default.
- W1966339928 hasConceptScore W1966339928C178790620 @default.
- W1966339928 hasConceptScore W1966339928C185592680 @default.
- W1966339928 hasConceptScore W1966339928C2776495794 @default.
- W1966339928 hasConceptScore W1966339928C2779081379 @default.
- W1966339928 hasConceptScore W1966339928C2993207723 @default.
- W1966339928 hasConceptScore W1966339928C509974204 @default.
- W1966339928 hasConceptScore W1966339928C540031477 @default.
- W1966339928 hasConceptScore W1966339928C70289976 @default.
- W1966339928 hasConceptScore W1966339928C71924100 @default.
- W1966339928 hasConceptScore W1966339928C7836513 @default.
- W1966339928 hasLocation W19663399281 @default.
- W1966339928 hasOpenAccess W1966339928 @default.
- W1966339928 hasPrimaryLocation W19663399281 @default.
- W1966339928 hasRelatedWork W1512268871 @default.
- W1966339928 hasRelatedWork W1536864538 @default.
- W1966339928 hasRelatedWork W1952813995 @default.
- W1966339928 hasRelatedWork W1963973526 @default.
- W1966339928 hasRelatedWork W1972974036 @default.
- W1966339928 hasRelatedWork W1986441241 @default.
- W1966339928 hasRelatedWork W2012023411 @default.
- W1966339928 hasRelatedWork W2059864448 @default.
- W1966339928 hasRelatedWork W2067002746 @default.
- W1966339928 hasRelatedWork W2072403698 @default.
- W1966339928 hasRelatedWork W2076142917 @default.
- W1966339928 hasRelatedWork W2098742764 @default.
- W1966339928 hasRelatedWork W2111349776 @default.
- W1966339928 hasRelatedWork W2112580440 @default.
- W1966339928 hasRelatedWork W2113664880 @default.
- W1966339928 hasRelatedWork W2151556517 @default.