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• W1966345333 abstract "Turnaround time for molecular diagnostic tests is critical in detecting infectious agents, in determining a patient's ability to metabolize a drug or drug class, and in detecting minimal residual disease. These applications would benefit from the development of a point-of-care device for nucleic acid extraction, amplification, and detection. The ideal device would have a low cost per test, use a disposable unit use device for all steps in the assay, be portable, and provide a result that requires no interpretation. The creation of such a device requires miniaturization of current technologies and the use of microfluidics, microarrays, and small-diameter capillary tubes to reduce reagent volumes and simplify heat conduction by convection during nucleic acid amplification. This ideal device may be available in 3 to 5 years and will revolutionize and expand the global availability of molecular diagnostic assays." @default.
• W1966345333 created "2016-06-24" @default.
• W1966345333 creator A5037513295 @default.
• W1966345333 creator A5062218665 @default.
• W1966345333 date "2009-09-01" @default.
• W1966345333 modified "2023-10-06" @default.
• W1966345333 title "Point-of-Care Testing and Molecular Diagnostics: Miniaturization Required" @default.
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• W1966345333 doi "https://doi.org/10.1016/j.cll.2009.06.013" @default.
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