Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966367079> ?p ?o ?g. }
- W1966367079 endingPage "67" @default.
- W1966367079 startingPage "53" @default.
- W1966367079 abstract "Despite the impressive literature describing atypical neural activation in visuoperceptual face processing regions in autism, almost nothing is known about whether these perturbations extend to more affective regions in the circuitry and whether they bear any relationship to symptom severity or atypical behavior. Using fMRI, we compared face-, object-, and house-related activation in adolescent males with high-functioning autism (HFA) and typically developing (TD) matched controls. HFA adolescents exhibited hypo-activation throughout the core visuoperceptual regions, particularly in the right hemisphere, as well as in some of the affective/motivational face-processing regions, including the posterior cingulate cortex and right anterior temporal lobe. Conclusions about the relative hyper- or hypo-activation of the amygdala depended on the nature of the contrast that was used to define the activation. Individual differences in symptom severity predicted the magnitude of face activation, particularly in the right fusiform gyrus. Also, among the HFA adolescents, face recognition performance predicted the magnitude of face activation in the right anterior temporal lobe, a region that supports face individuation in TD adults. Our findings reveal a systematic relation between the magnitude of neural dysfunction, severity of autism symptoms, and variation in face recognition behavior in adolescents with autism. In so doing, we uncover brain–behavior relations that underlie one of the most prominent social deficits in autism and help resolve discrepancies in the literature." @default.
- W1966367079 created "2016-06-24" @default.
- W1966367079 creator A5010132043 @default.
- W1966367079 creator A5022457751 @default.
- W1966367079 creator A5056030231 @default.
- W1966367079 creator A5056607871 @default.
- W1966367079 date "2015-01-01" @default.
- W1966367079 modified "2023-10-15" @default.
- W1966367079 title "Individual differences in symptom severity and behavior predict neural activation during face processing in adolescents with autism" @default.
- W1966367079 cites W1576453162 @default.
- W1966367079 cites W1588132147 @default.
- W1966367079 cites W1965892345 @default.
- W1966367079 cites W1972897873 @default.
- W1966367079 cites W1973118694 @default.
- W1966367079 cites W1977757700 @default.
- W1966367079 cites W1978609016 @default.
- W1966367079 cites W1980309199 @default.
- W1966367079 cites W1981316009 @default.
- W1966367079 cites W1983006628 @default.
- W1966367079 cites W1989079659 @default.
- W1966367079 cites W1990633935 @default.
- W1966367079 cites W2000454722 @default.
- W1966367079 cites W2004995289 @default.
- W1966367079 cites W2010246526 @default.
- W1966367079 cites W2011536087 @default.
- W1966367079 cites W2014688128 @default.
- W1966367079 cites W2016768311 @default.
- W1966367079 cites W2018926249 @default.
- W1966367079 cites W2020781956 @default.
- W1966367079 cites W2022111475 @default.
- W1966367079 cites W2025319978 @default.
- W1966367079 cites W2031371003 @default.
- W1966367079 cites W2038422711 @default.
- W1966367079 cites W2039929057 @default.
- W1966367079 cites W2043038916 @default.
- W1966367079 cites W2044266604 @default.
- W1966367079 cites W2044437189 @default.
- W1966367079 cites W2044941680 @default.
- W1966367079 cites W2045007565 @default.
- W1966367079 cites W2049227985 @default.
- W1966367079 cites W2052094880 @default.
- W1966367079 cites W2059179319 @default.
- W1966367079 cites W2063977089 @default.
- W1966367079 cites W2064526521 @default.
- W1966367079 cites W2068109107 @default.
- W1966367079 cites W2071862406 @default.
- W1966367079 cites W2071877993 @default.
- W1966367079 cites W2073367016 @default.
- W1966367079 cites W2086711445 @default.
- W1966367079 cites W2089413443 @default.
- W1966367079 cites W2094732962 @default.
- W1966367079 cites W2097775392 @default.
- W1966367079 cites W2098408283 @default.
- W1966367079 cites W2098958400 @default.
- W1966367079 cites W2099571672 @default.
- W1966367079 cites W2100254283 @default.
- W1966367079 cites W2101790396 @default.
- W1966367079 cites W2103444586 @default.
- W1966367079 cites W2105251885 @default.
- W1966367079 cites W2106700140 @default.
- W1966367079 cites W2106908564 @default.
- W1966367079 cites W2107663543 @default.
- W1966367079 cites W2109273508 @default.
- W1966367079 cites W2109332877 @default.
- W1966367079 cites W2111312054 @default.
- W1966367079 cites W2112896554 @default.
- W1966367079 cites W2113941552 @default.
- W1966367079 cites W2114691017 @default.
- W1966367079 cites W2118201036 @default.
- W1966367079 cites W2121825607 @default.
- W1966367079 cites W2122204760 @default.
- W1966367079 cites W2123329525 @default.
- W1966367079 cites W2123341385 @default.
- W1966367079 cites W2124807472 @default.
- W1966367079 cites W2126077087 @default.
- W1966367079 cites W2128061262 @default.
- W1966367079 cites W2128592952 @default.
- W1966367079 cites W2129825830 @default.
- W1966367079 cites W2133553417 @default.
- W1966367079 cites W2133663463 @default.
- W1966367079 cites W2139934183 @default.
- W1966367079 cites W2141273499 @default.
- W1966367079 cites W2149672898 @default.
- W1966367079 cites W2161072807 @default.
- W1966367079 cites W2161450501 @default.
- W1966367079 cites W2162250902 @default.
- W1966367079 cites W2163274894 @default.
- W1966367079 cites W2163470562 @default.
- W1966367079 cites W2163993943 @default.
- W1966367079 cites W2168282726 @default.
- W1966367079 doi "https://doi.org/10.1016/j.nicl.2014.11.003" @default.
- W1966367079 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4299957" @default.
- W1966367079 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25610767" @default.
- W1966367079 hasPublicationYear "2015" @default.
- W1966367079 type Work @default.
- W1966367079 sameAs 1966367079 @default.
- W1966367079 citedByCount "39" @default.
- W1966367079 countsByYear W19663670792015 @default.