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- W1966367473 abstract "The construction of a molecular mechanism capable of generating action potentials in lipid bilayers is described. — A protein called EIM obtained from enterobacter cloacae, forms cation selective channels which can be opened and closed by the membrane potential. In sphingomyelin-tocopherol membranes the membrane conductance changes over 3 — 4 orders of magnitude between —60 and + 25 mV. In an ionic concentration gradient the membranes generate a cationic resting potential of up to 70 mV. This potential acts as an applied potential and closes most of the channels. When protamine is added to a membrane containing EIM, the channels become anion selective" @default.
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- W1966367473 date "1980-04-01" @default.
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- W1966367473 title "Action Potentials in Lipid Bilayers" @default.
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- W1966367473 doi "https://doi.org/10.1002/bbpc.19800840408" @default.
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