FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966384392> ?p ?o ?g. }

• W1966384392 endingPage "39" @default.
• W1966384392 startingPage "30" @default.
• W1966384392 abstract "In contrast to the closely controlled phenomenon of plant senescence, very little is known about the molecular processes leading to ageing, which is understood as stochastic degeneration. In plants ageing apparently commences when cell division expires. To explore the relation between cell division and ageing, the expression of cell cycle control genes in the course of a batch culture of photoautotrophic cells of Chenopodium rubrum was studied. In a time‐span of 3 months this culture passes through the developmental phases: division (4 weeks), stationary (5 weeks) and ageing (3–4 weeks). Transcripts of 8 cell cycle control genes ( cyclins A/B , D2 and D3 , an A‐type CDKA and CDKB;1 , Rb‐Protein , E2F and of an inhibitor ICDK ) could be detected in all stages of the batch culture. Expression of CycD2 , CDKB;1 and Rb markedly declined with the transition from the division to the stationary phase of the cell culture and remained low until the cells died. Transcript levels of the A‐type CDK , cyclins A/B and D3 , as well as ICDK , passed through a maximum in the division phase but peaked again in the course of the stationary phase. Levels of the E2F transcript were high in the division and the early stationary phase and then stepwise declined. Addition of cytokinin plus auxin (2,4‐D) to the culture during the first week of the stationary phase resulted in a transitory resumption of cell division, or at least of the G1–S‐transition, concomitantly with a temporary increase in the transcript levels of CycD2 , CycD3 , CycA/B , CDKA and ICDK . Expression of Rb did not substantially change upon supply of the phytohormones and that of the CDKB;1 and E2F was even suppressed. The results show that in the C. rubrum batch culture both the G1‐S and the G2‐M transition were arrested after 4 weeks of cell culture and that this was set by the downregulation of the expression of CycD2 and Rb on the G1‐S‐ and of CDKB;1 on the G2‐M‐transition. Only the lowering of the CycD2 transcript level was reversible with cytokinin and 2,4‐D. The increase of the ICDK ‐transcript level during the stationary phase and in particular upon addition of the phytohormones is interpreted with regard to auxin‐triggered cell enlargement in the course of the stationary phase. A signal sequence is concluded, starting from the deterioration of the nutritional situation of the cells in the batch culture, and manifested by the decrease of the endogenous phytohormone levels, that results in a different expression of cell cycle control genes. Such a signal transduction cascade may include other components as well, and may additionally be affected by oxidative stress, which increases upon ageing." @default.
• W1966384392 created "2016-06-24" @default.
• W1966384392 creator A5008374583 @default.
• W1966384392 creator A5023829899 @default.
• W1966384392 creator A5026929389 @default.
• W1966384392 creator A5038281574 @default.
• W1966384392 date "2003-08-18" @default.
• W1966384392 modified "2023-10-16" @default.
• W1966384392 title "Expression of Cell Cycle Control factors in non‐dividing and ageing photoautotrophic plant cells" @default.
• W1966384392 cites W1508682879 @default.
• W1966384392 cites W1533562237 @default.
• W1966384392 cites W1575507552 @default.
• W1966384392 cites W1658682427 @default.
• W1966384392 cites W1963212435 @default.
• W1966384392 cites W1978808801 @default.
• W1966384392 cites W1986814752 @default.
• W1966384392 cites W2009930156 @default.
• W1966384392 cites W2011804093 @default.
• W1966384392 cites W2012202823 @default.
• W1966384392 cites W2022497783 @default.
• W1966384392 cites W2022613150 @default.
• W1966384392 cites W2026311140 @default.
• W1966384392 cites W2026824471 @default.
• W1966384392 cites W2034101399 @default.
• W1966384392 cites W2042787645 @default.
• W1966384392 cites W2048508491 @default.
• W1966384392 cites W2050819030 @default.
• W1966384392 cites W2051239814 @default.
• W1966384392 cites W2054262102 @default.
• W1966384392 cites W2059620074 @default.
• W1966384392 cites W2063954820 @default.
• W1966384392 cites W2066052665 @default.
• W1966384392 cites W2072702125 @default.
• W1966384392 cites W2077241234 @default.
• W1966384392 cites W2082173246 @default.
• W1966384392 cites W2082863424 @default.
• W1966384392 cites W2087165791 @default.
• W1966384392 cites W2087646696 @default.
• W1966384392 cites W2091543204 @default.
• W1966384392 cites W2101861123 @default.
• W1966384392 cites W2107358212 @default.
• W1966384392 cites W2108482850 @default.
• W1966384392 cites W2110435452 @default.
• W1966384392 cites W2111935289 @default.
• W1966384392 cites W2112078030 @default.
• W1966384392 cites W2135795135 @default.
• W1966384392 cites W2145444730 @default.
• W1966384392 cites W2156004605 @default.
• W1966384392 cites W2158303258 @default.
• W1966384392 cites W2159379816 @default.
• W1966384392 cites W2164181759 @default.
• W1966384392 cites W2170758324 @default.
• W1966384392 cites W2189899083 @default.
• W1966384392 cites W367367718 @default.
• W1966384392 cites W4232925121 @default.
• W1966384392 cites W4237730561 @default.
• W1966384392 cites W4238115908 @default.
• W1966384392 cites W4243975953 @default.
• W1966384392 cites W4245757157 @default.
• W1966384392 doi "https://doi.org/10.1034/j.1399-3054.2003.00169.x" @default.
• W1966384392 hasPublicationYear "2003" @default.
• W1966384392 type Work @default.
• W1966384392 sameAs 1966384392 @default.
• W1966384392 citedByCount "8" @default.
• W1966384392 countsByYear W19663843922014 @default.
• W1966384392 countsByYear W19663843922016 @default.
• W1966384392 countsByYear W19663843922020 @default.
• W1966384392 crossrefType "journal-article" @default.
• W1966384392 hasAuthorship W1966384392A5008374583 @default.
• W1966384392 hasAuthorship W1966384392A5023829899 @default.
• W1966384392 hasAuthorship W1966384392A5026929389 @default.
• W1966384392 hasAuthorship W1966384392A5038281574 @default.
• W1966384392 hasConcept C104317684 @default.
• W1966384392 hasConcept C120089663 @default.
• W1966384392 hasConcept C1491633281 @default.
• W1966384392 hasConcept C207778908 @default.
• W1966384392 hasConcept C29537977 @default.
• W1966384392 hasConcept C500499127 @default.
• W1966384392 hasConcept C522857546 @default.
• W1966384392 hasConcept C54355233 @default.
• W1966384392 hasConcept C59822182 @default.
• W1966384392 hasConcept C83258922 @default.
• W1966384392 hasConcept C85813293 @default.
• W1966384392 hasConcept C86803240 @default.
• W1966384392 hasConcept C95444343 @default.
• W1966384392 hasConceptScore W1966384392C104317684 @default.
• W1966384392 hasConceptScore W1966384392C120089663 @default.
• W1966384392 hasConceptScore W1966384392C1491633281 @default.
• W1966384392 hasConceptScore W1966384392C207778908 @default.
• W1966384392 hasConceptScore W1966384392C29537977 @default.
• W1966384392 hasConceptScore W1966384392C500499127 @default.
• W1966384392 hasConceptScore W1966384392C522857546 @default.
• W1966384392 hasConceptScore W1966384392C54355233 @default.
• W1966384392 hasConceptScore W1966384392C59822182 @default.
• W1966384392 hasConceptScore W1966384392C83258922 @default.
• W1966384392 hasConceptScore W1966384392C85813293 @default.
• W1966384392 hasConceptScore W1966384392C86803240 @default.
• W1966384392 hasConceptScore W1966384392C95444343 @default.

• next