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- W1966446087 abstract "The ability of mismatch binding proteins, in particular the Escherichia coli MutS protein, to bind DNA containing mismatched base pairs or one to four unpaired bases makes them ideally suited to use in mutation/polymorphism detection assays. Several methods, including nuclease protection, band shift, and filter binding assays, have been employed with varying degrees of success. New assays, including genemic mismatch scanning, immobilized mismatch binding protein, and direct detection of mismatch binding protein, are being developed and appear promising. Mismatch binding protein-based assays have the potential for widespread use in both basic research and clinical applications." @default.
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- W1966446087 date "1995-04-01" @default.
- W1966446087 modified "2023-10-17" @default.
- W1966446087 title "Mismatch Binding Protein-Based Mutation Detection Systems" @default.
- W1966446087 doi "https://doi.org/10.1006/meth.1995.1025" @default.
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