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- W1966452389 abstract "Protein kinase C (PKC) proteins are a group of well-conserved, intracellular signaling enzymes expressed in all cells and tissues, including immune cells. Much of the molecular insight into PKC immunobiology has been gleaned from studies using PKC gene (Prkc) knockout mice and the analysis of different disease models in these animals. More-recent studies have revealed that PKCs also have crucial roles in the pathogenesis of human immune disorders. Therefore, strategies to modulate the functions of PKC enzymes could have a major impact on the treatment and therapies of autoimmune diseases and other immune disorders." @default.
- W1966452389 created "2016-06-24" @default.
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- W1966452389 date "2014-08-01" @default.
- W1966452389 modified "2023-09-23" @default.
- W1966452389 title "Protein kinase C inhibitors for immune disorders" @default.
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- W1966452389 doi "https://doi.org/10.1016/j.drudis.2014.05.008" @default.
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