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- W1966474944 abstract "The self-interaction of two deoxydinucleotides, pdG-dC and pdG-dT, was studied (in aqueous solution) by 100 MHz FT NMR spectroscopy. Concentration studies show that the self-complementary pdG-dC forms hydrogen bonded complexes. An analysis based on the concentration dependence of the chemical shift of the guanine amino protons strongly suggests that hydrogen bonded dimer formation occurs with a K for the dimerization equilibrium of 7.8 ± 0.7 M−1. On the other hand, the non-self-complementary pdG-dT does not give evidence of similar complex formation in the same concentration range which thus illustrates the importance of complementarity in the formation of hydrogen bonded complexes of deoxydinucleotides. Further impetus is therefore provided for the use of dinucleotides in modeling interactions common to nucleic acids." @default.
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- W1966474944 date "1975-02-01" @default.
- W1966474944 modified "2023-09-23" @default.
- W1966474944 title "Nuclear magnetic resonance studies of hydrogen bonded complexes of oligonucleotides in aqueous solution. I. pdG-dC and pdG-dT" @default.
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- W1966474944 doi "https://doi.org/10.1016/0006-291x(75)90425-8" @default.
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