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- W1966509973 abstract "Nuclear factor of activated T cell (NFAT) is a ubiquitous regulator involved in multiple biological processes. Here, we demonstrate that NFAT is temporally required in the developing atrial myocardium between embryonic day 14 and P0 (birth). Inhibition of NFAT activity by conditional expression of dominant-negative NFAT causes thinning of the atrial myocardium. The thin myocardium exhibits severe sarcomere disorganization and reduced expression of cardiac troponin-I (cTnI) and cardiac troponin-T (cTnT). Promoter analysis indicates that NFAT binds to and regulates transcription of the cTnI and the cTnT genes. Thus, regulation of cytoskeletal protein gene expression by NFAT may be important for the structural architecture of the developing atrial myocardium." @default.
- W1966509973 created "2016-06-24" @default.
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- W1966509973 date "2003-06-09" @default.
- W1966509973 modified "2023-10-02" @default.
- W1966509973 title "Requirement of transcription factor NFAT in developing atrial myocardium" @default.
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- W1966509973 cites W1607134889 @default.
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- W1966509973 doi "https://doi.org/10.1083/jcb.200301058" @default.
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