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- W1966523718 abstract "Effects of xylitol on steroidogenesis by hypophysectomized rat adrenals have been studied. A considerable stimulation on corticosterone formation from labeled cholesterol by quartered adrenals of hypophysectomized rats has been observed by addition of 20 mM xylitol corresponding to stimulation by ACTH. Xylitol also caused an increase in corticosteroidogenesis by homogenates of hypophysectomized rat adrenals, comparable to the homogenates fortified with exogenous NADPH. A possibility that xylitol might stimulate an alternative NADPH generating system required for steroidogenesis in the uronic acid way of adrenals, in which a poor availability of NADPH generating depending on the pentose phosphate way had been induced by hypophysectomy was discussed." @default.
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- W1966523718 date "1970-09-01" @default.
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- W1966523718 title "Effect of xylitol on steroidogenesis by rat adrenal gland" @default.
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