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• W1966526136 endingPage "21" @default.
• W1966526136 startingPage "1" @default.
• W1966526136 abstract "Toll-like receptors (TLRs) are a member of the innate immune system. TLRs detect invading pathogens through the pathogen-associated molecular patterns (PAMPs) recognition and play an essential role in the host defense. TLRs can also sense a large number of endogenous molecules with the damage-associated molecular patterns (DAMPs) that are produced under various injurious conditions. Animal studies of the last decade have demonstrated that TLR signaling contributes to the pathogenesis of the critical cardiac conditions, where myocardial inflammation plays a prominent role, such as ischemic myocardial injury, myocarditis, and septic cardiomyopathy. This paper reviews the animal data on (1) TLRs, TLR ligands, and the signal transduction system and (2) the important role of TLR signaling in these critical cardiac conditions." @default.
• W1966526136 created "2016-06-24" @default.
• W1966526136 creator A5018221928 @default.
• W1966526136 creator A5089869726 @default.
• W1966526136 date "2011-01-01" @default.
• W1966526136 modified "2023-10-18" @default.
• W1966526136 title "Toll-Like Receptors and Myocardial Inflammation" @default.
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