Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966553058> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W1966553058 endingPage "33" @default.
- W1966553058 startingPage "19" @default.
- W1966553058 abstract "Incorporation of 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2), the principal mutagen in a tryptophan pyrolysate, into bovine serum albumin was catalyzed by myeloperoxidase. Hydrogen peroxide was essential for the incorporation reaction and albumin was required for optimal incorporation of Trp-P-2 into protein. Other various proteins, such as histone, lysozyme, cytochrome c, and gamma-globulin could also incorporate Trp-P-2, but poly(L-Arg), poly(L-Lys), and poly(L-Glu) could not. The incorporation of Trp-P-2 into albumin was inhibited by L-tyrosine and L-tryptophan, but not by other amino acids. Trp-P-2 incorporated into albumin was not released from the protein by treatment with 0.3 N HCl, or 0.3 N NaOH for 2 h at 35 degrees C, or with 1% sodium dodecylsulfate for 2.5 min at 100 degrees C. On electrophoresis on polyacrylamide containing sodium dodecylsulfate or urea and on chromatography on Sepharose CL-6B in 6 M guanidine/HCl, Trp-P-2 incorporated into albumin or lysozyme migrated with these proteins. These findings indicate that Trp-P-2 is covalently bound to these acceptor proteins." @default.
- W1966553058 created "2016-06-24" @default.
- W1966553058 creator A5044588214 @default.
- W1966553058 creator A5058630840 @default.
- W1966553058 creator A5063644416 @default.
- W1966553058 date "1980-12-01" @default.
- W1966553058 modified "2023-10-18" @default.
- W1966553058 title "Myeloperoxidase-catalyzed binding of 3-amino-1-methyl-5H-pyrido[4,3-b]indole, a tryptophan pyrolysis product, to protein" @default.
- W1966553058 cites W128390068 @default.
- W1966553058 cites W1512590156 @default.
- W1966553058 cites W1538437514 @default.
- W1966553058 cites W1972924854 @default.
- W1966553058 cites W1973856086 @default.
- W1966553058 cites W1978181982 @default.
- W1966553058 cites W1996066714 @default.
- W1966553058 cites W2003225177 @default.
- W1966553058 cites W2012002560 @default.
- W1966553058 cites W2022196188 @default.
- W1966553058 cites W2027571842 @default.
- W1966553058 cites W2034277598 @default.
- W1966553058 cites W2049618878 @default.
- W1966553058 cites W2058170465 @default.
- W1966553058 cites W2062080157 @default.
- W1966553058 cites W2068604977 @default.
- W1966553058 cites W2081953645 @default.
- W1966553058 cites W2083661681 @default.
- W1966553058 cites W2100837269 @default.
- W1966553058 cites W2111301002 @default.
- W1966553058 cites W2138125869 @default.
- W1966553058 cites W2154061135 @default.
- W1966553058 cites W2314466252 @default.
- W1966553058 doi "https://doi.org/10.1016/0009-2797(80)90041-1" @default.
- W1966553058 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6254679" @default.
- W1966553058 hasPublicationYear "1980" @default.
- W1966553058 type Work @default.
- W1966553058 sameAs 1966553058 @default.
- W1966553058 citedByCount "8" @default.
- W1966553058 crossrefType "journal-article" @default.
- W1966553058 hasAuthorship W1966553058A5044588214 @default.
- W1966553058 hasAuthorship W1966553058A5058630840 @default.
- W1966553058 hasAuthorship W1966553058A5063644416 @default.
- W1966553058 hasConcept C185592680 @default.
- W1966553058 hasConcept C192527728 @default.
- W1966553058 hasConcept C2776125364 @default.
- W1966553058 hasConcept C2776706248 @default.
- W1966553058 hasConcept C2776966407 @default.
- W1966553058 hasConcept C2779463914 @default.
- W1966553058 hasConcept C515207424 @default.
- W1966553058 hasConcept C55493867 @default.
- W1966553058 hasConcept C86807702 @default.
- W1966553058 hasConceptScore W1966553058C185592680 @default.
- W1966553058 hasConceptScore W1966553058C192527728 @default.
- W1966553058 hasConceptScore W1966553058C2776125364 @default.
- W1966553058 hasConceptScore W1966553058C2776706248 @default.
- W1966553058 hasConceptScore W1966553058C2776966407 @default.
- W1966553058 hasConceptScore W1966553058C2779463914 @default.
- W1966553058 hasConceptScore W1966553058C515207424 @default.
- W1966553058 hasConceptScore W1966553058C55493867 @default.
- W1966553058 hasConceptScore W1966553058C86807702 @default.
- W1966553058 hasIssue "1" @default.
- W1966553058 hasLocation W19665530581 @default.
- W1966553058 hasLocation W19665530582 @default.
- W1966553058 hasOpenAccess W1966553058 @default.
- W1966553058 hasPrimaryLocation W19665530581 @default.
- W1966553058 hasRelatedWork W133454639 @default.
- W1966553058 hasRelatedWork W1964136309 @default.
- W1966553058 hasRelatedWork W1966553058 @default.
- W1966553058 hasRelatedWork W1975949037 @default.
- W1966553058 hasRelatedWork W1999482679 @default.
- W1966553058 hasRelatedWork W2070942533 @default.
- W1966553058 hasRelatedWork W2155327588 @default.
- W1966553058 hasRelatedWork W2394206780 @default.
- W1966553058 hasRelatedWork W4312565954 @default.
- W1966553058 hasRelatedWork W628094965 @default.
- W1966553058 hasVolume "33" @default.
- W1966553058 isParatext "false" @default.
- W1966553058 isRetracted "false" @default.
- W1966553058 magId "1966553058" @default.
- W1966553058 workType "article" @default.