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• W1966571789 abstract "Adrenal infarction is a well-recognized complication of diagnostic adrenal phlebography and if it occurs bilaterally it may lead to adrenal insufficiency (Eagan and Page, 1971; Fisher et al., 1971; Taylor and Sachs, 1976). This is because the delicate adrenal veins are easily obstructed and over-distended during the injection of contrast medium, leading to venous rupture and thrombosis with secondary adrenal infarction. Remission of Cushing's syndrome, apparently due to adrenal adenoma, has been reported after diagnostic adrenal phlebography (Fellerman et al., 1970; Jørgensen and Stiris, 1974), and the ectopic ACTH syndrome has been controlled in two reported cases by intentional bilateral venous infarction (Eddy et al., 1973; Rogove et al., 1976). We report the successful use of adrenal venous infarction in a patient with severe life-threatening ACTH-dependent Cushing's syndrome. The procedure ameliorated the hypercortisolism as a temporary measure in preparation for definitive surgical adrenalectomy. A 26-year-old man was referred to us in October 1979 with extremely severe Cushing's syndrome. Four months previously a diagnosis of hypercortisolism had been made at his local hospital. Adrenal venography had shown an enlarged left adrenal gland but it had been impossible to cannulate the right adrenal vein. A left adrenal carcinoma was suspected and that gland was removed through a mid-line abdominal incision. The histology showed adrenal hyperplasia with no evidence of malignancy. Post-operatively his condition continued to worsen and he became extremely ill with severe hypokalaemia, and greatly elevated plasma cortisol, urinary 17-oxosteroid and 17-hydroxysteroid levels." @default.
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• W1966571789 date "1981-10-01" @default.
• W1966571789 modified "2023-09-25" @default.
• W1966571789 title "Therapeutic adrenal venous infarction in ACTH-dependent Cushing's syndrome" @default.
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• W1966571789 doi "https://doi.org/10.1259/0007-1285-54-646-912" @default.
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