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- W1966597908 abstract "Summary Helicobacter pylori infection of the stomach is associated with gastritis and peptic ulceration and may be causative. A noninvasive test for this organism might be useful in managing some patients with dyspepsia without the need for further investigation. We have evaluated a new commercially available serological test (Helico-G ELISA, Porton Cambridge, UK) for this infection to assess its diagnostic accuracy in a retrospective study of 115 patients with non-ulcer dyspepsia. Sixty-three of these patients (55%) were found to have H. pylori infection and gastritis on histology. A sensitivity of 81% and specificity of 90% were obtained. No significant fall in the antibody titres was found in a subgroup of 15 patients who were selected to complete a course of triple therapy despite significant improvement in their dyspepsia score and confirmed eradication of H. pylori organism in 80% of these patients. We conclude that the test has limited value in aiding clinical decision of managing patients with dyspepsia." @default.
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- W1966597908 title "Evaluation of a commercial enzyme-linked immunosorbent assay (ELISA) kit for serological diagnosis of <i>Helicobacter pylori</i> infection in a group of non-ulcer dyspepsia sufferers" @default.
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- W1966597908 doi "https://doi.org/10.1136/pgmj.69.812.456" @default.
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