FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966614661> ?p ?o ?g. }

• W1966614661 endingPage "231" @default.
• W1966614661 startingPage "225" @default.
• W1966614661 abstract "Because the association of hypertriglyceridemia and premature atherosclerosis is not due to the direct effects of the triglyceride molecule itself, we studied the effects of increased plasma triglyceride-rich lipoproteins on the composition and structure of low density lipoprotein (LDL) and high density lipoprotein (HDL). We found profound changes in the core and surface domains of both lipoproteins with increasing triglyceridemia. Core cholesterol esters were progressively depleted and replaced by triglyceride molecules. Highly significant negative correlations were found between cholesterol ester/protein ratios (r = -0.64 for LDL and -0.58 for HDL (p less than 0.001); positive correlations were found for triglyceride/protein ratios (r = 0.62 for LDL and 0.58 for HDL) and for triglyceride/cholesterol ester ratios (r = 0.70 for LDL and 0.83 for HDL) when these variables were assayed as a function of plasma triglyceride concentrations. With severe hypertriglyceridemia, triglyceride/cholesterol ester ratios of more than 1.0 were consistently observed (normal, less than 0.02). This leads to an underestimation of LDL and HDL levels when cholesterol alone is measured. At the surface, LDL and HDL were depleted of phospholipid and free cholesterol, with a relative enrichment of protein. These changes can be explained on the basis of high levels of plasma triglyceride-rich lipoproteins serving as acceptors for cholesterol esters and other constituents from LDL and HDL. Concomitantly, triglycerides are transferred to LDL and HDL. These transfer processes are likely to be mediated by the activity of lipid transfer proteins present in human plasma." @default.
• W1966614661 created "2016-06-24" @default.
• W1966614661 creator A5023885084 @default.
• W1966614661 creator A5033182693 @default.
• W1966614661 creator A5052483787 @default.
• W1966614661 creator A5059089783 @default.
• W1966614661 creator A5086092158 @default.
• W1966614661 date "1984-05-01" @default.
• W1966614661 modified "2023-10-13" @default.
• W1966614661 title "Plasma triglyceride determines structure-composition in low and high density lipoproteins." @default.
• W1966614661 cites W1512559452 @default.
• W1966614661 cites W1584290267 @default.
• W1966614661 cites W1775749144 @default.
• W1966614661 cites W1908293130 @default.
• W1966614661 cites W1963144433 @default.
• W1966614661 cites W1964513423 @default.
• W1966614661 cites W1964941215 @default.
• W1966614661 cites W1989258056 @default.
• W1966614661 cites W1991997766 @default.
• W1966614661 cites W1994967652 @default.
• W1966614661 cites W2004410658 @default.
• W1966614661 cites W2009789367 @default.
• W1966614661 cites W2040164369 @default.
• W1966614661 cites W2041307432 @default.
• W1966614661 cites W2046715868 @default.
• W1966614661 cites W2060004345 @default.
• W1966614661 cites W2103568278 @default.
• W1966614661 cites W2109011306 @default.
• W1966614661 cites W2112698709 @default.
• W1966614661 cites W2113239638 @default.
• W1966614661 cites W2145629269 @default.
• W1966614661 cites W2158385780 @default.
• W1966614661 cites W2168526937 @default.
• W1966614661 cites W2186697990 @default.
• W1966614661 cites W2253540608 @default.
• W1966614661 cites W2327887667 @default.
• W1966614661 cites W2341873670 @default.
• W1966614661 cites W2342705022 @default.
• W1966614661 cites W2404891775 @default.
• W1966614661 cites W2419582404 @default.
• W1966614661 cites W2588417043 @default.
• W1966614661 cites W3216143596 @default.
• W1966614661 doi "https://doi.org/10.1161/01.atv.4.3.225" @default.
• W1966614661 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6712536" @default.
• W1966614661 hasPublicationYear "1984" @default.
• W1966614661 type Work @default.
• W1966614661 sameAs 1966614661 @default.
• W1966614661 citedByCount "283" @default.
• W1966614661 countsByYear W19666146612012 @default.
• W1966614661 countsByYear W19666146612013 @default.
• W1966614661 countsByYear W19666146612015 @default.
• W1966614661 countsByYear W19666146612016 @default.
• W1966614661 countsByYear W19666146612017 @default.
• W1966614661 countsByYear W19666146612018 @default.
• W1966614661 countsByYear W19666146612019 @default.
• W1966614661 countsByYear W19666146612021 @default.
• W1966614661 countsByYear W19666146612022 @default.
• W1966614661 countsByYear W19666146612023 @default.
• W1966614661 crossrefType "journal-article" @default.
• W1966614661 hasAuthorship W1966614661A5023885084 @default.
• W1966614661 hasAuthorship W1966614661A5033182693 @default.
• W1966614661 hasAuthorship W1966614661A5052483787 @default.
• W1966614661 hasAuthorship W1966614661A5059089783 @default.
• W1966614661 hasAuthorship W1966614661A5086092158 @default.
• W1966614661 hasBestOaLocation W19666146611 @default.
• W1966614661 hasConcept C126322002 @default.
• W1966614661 hasConcept C134018914 @default.
• W1966614661 hasConcept C185592680 @default.
• W1966614661 hasConcept C2776919658 @default.
• W1966614661 hasConcept C2778163477 @default.
• W1966614661 hasConcept C2778913445 @default.
• W1966614661 hasConcept C2778918659 @default.
• W1966614661 hasConcept C2780072125 @default.
• W1966614661 hasConcept C2780541478 @default.
• W1966614661 hasConcept C41625074 @default.
• W1966614661 hasConcept C55493867 @default.
• W1966614661 hasConcept C71924100 @default.
• W1966614661 hasConcept C86803240 @default.
• W1966614661 hasConceptScore W1966614661C126322002 @default.
• W1966614661 hasConceptScore W1966614661C134018914 @default.
• W1966614661 hasConceptScore W1966614661C185592680 @default.
• W1966614661 hasConceptScore W1966614661C2776919658 @default.
• W1966614661 hasConceptScore W1966614661C2778163477 @default.
• W1966614661 hasConceptScore W1966614661C2778913445 @default.
• W1966614661 hasConceptScore W1966614661C2778918659 @default.
• W1966614661 hasConceptScore W1966614661C2780072125 @default.
• W1966614661 hasConceptScore W1966614661C2780541478 @default.
• W1966614661 hasConceptScore W1966614661C41625074 @default.
• W1966614661 hasConceptScore W1966614661C55493867 @default.
• W1966614661 hasConceptScore W1966614661C71924100 @default.
• W1966614661 hasConceptScore W1966614661C86803240 @default.
• W1966614661 hasIssue "3" @default.
• W1966614661 hasLocation W19666146611 @default.
• W1966614661 hasLocation W19666146612 @default.
• W1966614661 hasOpenAccess W1966614661 @default.
• W1966614661 hasPrimaryLocation W19666146611 @default.
• W1966614661 hasRelatedWork W1988795417 @default.
• W1966614661 hasRelatedWork W2012789085 @default.

• next