FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966649704> ?p ?o ?g. }

• W1966649704 endingPage "1364" @default.
• W1966649704 startingPage "1351" @default.
• W1966649704 abstract "Abstract Comparative genomics provides a powerful tool for the identification of genes that encode traits shared between crop plants and model organisms. Pathogen resistance conferred by plant R genes of the nucleotide-binding–leucine-rich-repeat (NB–LRR) class is one such trait with great agricultural importance that occupies a critical position in understanding fundamental processes of pathogen detection and coevolution. The proposed rapid rearrangement of R genes in genome evolution would make comparative approaches tenuous. Here, we test the hypothesis that orthology is predictive of R-gene genomic location in the Solanaceae using the pepper R gene Bs2. Homologs of Bs2 were compared in terms of sequence and gene and protein architecture. Comparative mapping demonstrated that Bs2 shared macrosynteny with R genes that best fit criteria determined to be its orthologs. Analysis of the genomic sequence encompassing solanaceous R genes revealed the magnitude of transposon insertions and local duplications that resulted in the expansion of the Bs2 intron to 27 kb and the frequently detected duplications of the 5′-end of R genes. However, these duplications did not impact protein expression or function in transient assays. Taken together, our results support a conservation of synteny for NB–LRR genes and further show that their distribution in the genome has been consistent with global rearrangements." @default.
• W1966649704 created "2016-06-24" @default.
• W1966649704 creator A5001322317 @default.
• W1966649704 creator A5033292381 @default.
• W1966649704 creator A5044932741 @default.
• W1966649704 creator A5053458834 @default.
• W1966649704 creator A5078391644 @default.
• W1966649704 creator A5084403759 @default.
• W1966649704 creator A5085172839 @default.
• W1966649704 creator A5085287011 @default.
• W1966649704 creator A5086027154 @default.
• W1966649704 date "2009-08-01" @default.
• W1966649704 modified "2023-09-23" @default.
• W1966649704 title "The Fractionated Orthology of <i>Bs2</i> and <i>Rx</i>/<i>Gpa2</i> Supports Shared Synteny of Disease Resistance in the Solanaceae" @default.
• W1966649704 cites W1515628079 @default.
• W1966649704 cites W1518701384 @default.
• W1966649704 cites W1796126005 @default.
• W1966649704 cites W1820473322 @default.
• W1966649704 cites W1821074866 @default.
• W1966649704 cites W1925391342 @default.
• W1966649704 cites W1966036234 @default.
• W1966649704 cites W1969865366 @default.
• W1966649704 cites W1975304761 @default.
• W1966649704 cites W1977322059 @default.
• W1966649704 cites W1981652772 @default.
• W1966649704 cites W1984675152 @default.
• W1966649704 cites W1984966768 @default.
• W1966649704 cites W1996019107 @default.
• W1966649704 cites W2000271281 @default.
• W1966649704 cites W2002459418 @default.
• W1966649704 cites W2004231420 @default.
• W1966649704 cites W2007542569 @default.
• W1966649704 cites W2008217004 @default.
• W1966649704 cites W2008884012 @default.
• W1966649704 cites W2015546050 @default.
• W1966649704 cites W2018087971 @default.
• W1966649704 cites W2018431232 @default.
• W1966649704 cites W2024645073 @default.
• W1966649704 cites W2035738152 @default.
• W1966649704 cites W2036295979 @default.
• W1966649704 cites W2038045805 @default.
• W1966649704 cites W2043288715 @default.
• W1966649704 cites W2048869876 @default.
• W1966649704 cites W2051110111 @default.
• W1966649704 cites W2052136236 @default.
• W1966649704 cites W2057459472 @default.
• W1966649704 cites W2063070384 @default.
• W1966649704 cites W2067971481 @default.
• W1966649704 cites W2068034316 @default.
• W1966649704 cites W2071769268 @default.
• W1966649704 cites W2074512572 @default.
• W1966649704 cites W2079231119 @default.
• W1966649704 cites W2082368599 @default.
• W1966649704 cites W2095538892 @default.
• W1966649704 cites W2098749551 @default.
• W1966649704 cites W2099489028 @default.
• W1966649704 cites W2100464143 @default.
• W1966649704 cites W2100684388 @default.
• W1966649704 cites W2104789942 @default.
• W1966649704 cites W2105850758 @default.
• W1966649704 cites W2108624927 @default.
• W1966649704 cites W2108780882 @default.
• W1966649704 cites W2110020535 @default.
• W1966649704 cites W2113441838 @default.
• W1966649704 cites W2114743740 @default.
• W1966649704 cites W2114955290 @default.
• W1966649704 cites W2121096658 @default.
• W1966649704 cites W2121711582 @default.
• W1966649704 cites W2122743214 @default.
• W1966649704 cites W2123420139 @default.
• W1966649704 cites W2123679376 @default.
• W1966649704 cites W2126841200 @default.
• W1966649704 cites W2129508689 @default.
• W1966649704 cites W2130699672 @default.
• W1966649704 cites W2133126366 @default.
• W1966649704 cites W2138405903 @default.
• W1966649704 cites W2139134943 @default.
• W1966649704 cites W2140177375 @default.
• W1966649704 cites W2141184931 @default.
• W1966649704 cites W2144932443 @default.
• W1966649704 cites W2145692261 @default.
• W1966649704 cites W2148801333 @default.
• W1966649704 cites W2155218146 @default.
• W1966649704 cites W2155592637 @default.
• W1966649704 cites W2156434383 @default.
• W1966649704 cites W2157044094 @default.
• W1966649704 cites W2160155425 @default.
• W1966649704 cites W2160910949 @default.
• W1966649704 cites W2162069196 @default.
• W1966649704 cites W2165676126 @default.
• W1966649704 cites W2167251717 @default.
• W1966649704 cites W2169929045 @default.
• W1966649704 cites W4254813272 @default.
• W1966649704 doi "https://doi.org/10.1534/genetics.109.101022" @default.
• W1966649704 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2728872" @default.
• W1966649704 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19474202" @default.
• W1966649704 hasPublicationYear "2009" @default.
• W1966649704 type Work @default.

• next