FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966658797> ?p ?o ?g. }

• W1966658797 endingPage "1504" @default.
• W1966658797 startingPage "1498" @default.
• W1966658797 abstract "Abstract: The presence of glycogen in astroglia‐rich primary cultures derived from the brains of newborn rats depends on the availability of glucose in the culture medium. On glucose deprivation, glycogen vanishes from the astroglial cultures. This decrease of glycogen content is completely prevented if 2‐deoxyglucose in a concentration of > 1 m M or 1,5‐gluconolactone (20 m M ) is present in the culture medium. 2‐Deoxyglucose itself or 3‐ O ‐methylglucose, a glucose derivative that is not phosphorylated by hexokinase, does not reduce the activity of glycogen phosphorylase purified from bovine brain or in the homogenate of astroglia‐rich rat primary cultures. In contrast, deoxyglucose‐6‐phosphate strongly inhibits the glycogen phosphorylase activities of the preparations. Half‐maximal effects were obtained at deoxyglucose‐6‐phosphate concentrations of 0.75 (phosphorylase a, astroglial culture), 5 (phosphorylase b, astroglial culture), 2 (phosphorylase a, bovine brain), or 9 m M (phosphorylase b, bovine brain). Thus, the block of glycogen degradation in these cells appears to be due to inhibition of glycogen phosphorylase by deoxyglucose‐6‐phosphate rather than deoxyglucose itself. These results suggest that glucose‐6‐phosphate, rather than glucose, acts as a physiological negative feedback regulator of the brain isoenzyme of phosphorylase and thus of glycogen degradation in astrocytes." @default.
• W1966658797 created "2016-06-24" @default.
• W1966658797 creator A5020958512 @default.
• W1966658797 creator A5077770397 @default.
• W1966658797 date "1993-04-01" @default.
• W1966658797 modified "2023-09-29" @default.
• W1966658797 title "Inhibition by 2-Deoxyglucose and 1,5-Gluconolactone of Glycogen Mobilization in Astroglia-Rich Primary Cultures" @default.
• W1966658797 cites W1259543534 @default.
• W1966658797 cites W1481582702 @default.
• W1966658797 cites W1565787013 @default.
• W1966658797 cites W1614353075 @default.
• W1966658797 cites W1775749144 @default.
• W1966658797 cites W1978007056 @default.
• W1966658797 cites W1979250477 @default.
• W1966658797 cites W1984976831 @default.
• W1966658797 cites W1985949509 @default.
• W1966658797 cites W1986873509 @default.
• W1966658797 cites W1992496199 @default.
• W1966658797 cites W2013195856 @default.
• W1966658797 cites W2059675585 @default.
• W1966658797 cites W2064139713 @default.
• W1966658797 cites W2067502143 @default.
• W1966658797 cites W2067981725 @default.
• W1966658797 cites W2068669272 @default.
• W1966658797 cites W2070417335 @default.
• W1966658797 cites W2071122107 @default.
• W1966658797 cites W2073887637 @default.
• W1966658797 cites W2082343153 @default.
• W1966658797 cites W2083132249 @default.
• W1966658797 cites W2090306035 @default.
• W1966658797 cites W2131059217 @default.
• W1966658797 cites W2144946796 @default.
• W1966658797 cites W2147242060 @default.
• W1966658797 cites W2151913862 @default.
• W1966658797 cites W2154116140 @default.
• W1966658797 cites W273676533 @default.
• W1966658797 doi "https://doi.org/10.1111/j.1471-4159.1993.tb03313.x" @default.
• W1966658797 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8455036" @default.
• W1966658797 hasPublicationYear "1993" @default.
• W1966658797 type Work @default.
• W1966658797 sameAs 1966658797 @default.
• W1966658797 citedByCount "26" @default.
• W1966658797 countsByYear W19666587972013 @default.
• W1966658797 countsByYear W19666587972014 @default.
• W1966658797 countsByYear W19666587972015 @default.
• W1966658797 countsByYear W19666587972019 @default.
• W1966658797 crossrefType "journal-article" @default.
• W1966658797 hasAuthorship W1966658797A5020958512 @default.
• W1966658797 hasAuthorship W1966658797A5077770397 @default.
• W1966658797 hasConcept C109384507 @default.
• W1966658797 hasConcept C126322002 @default.
• W1966658797 hasConcept C134018914 @default.
• W1966658797 hasConcept C181199279 @default.
• W1966658797 hasConcept C185592680 @default.
• W1966658797 hasConcept C192118531 @default.
• W1966658797 hasConcept C195147555 @default.
• W1966658797 hasConcept C20251656 @default.
• W1966658797 hasConcept C204779464 @default.
• W1966658797 hasConcept C2777499176 @default.
• W1966658797 hasConcept C2777790778 @default.
• W1966658797 hasConcept C2779826832 @default.
• W1966658797 hasConcept C2780909259 @default.
• W1966658797 hasConcept C55493867 @default.
• W1966658797 hasConcept C62231903 @default.
• W1966658797 hasConcept C71924100 @default.
• W1966658797 hasConcept C86803240 @default.
• W1966658797 hasConcept C9262364 @default.
• W1966658797 hasConceptScore W1966658797C109384507 @default.
• W1966658797 hasConceptScore W1966658797C126322002 @default.
• W1966658797 hasConceptScore W1966658797C134018914 @default.
• W1966658797 hasConceptScore W1966658797C181199279 @default.
• W1966658797 hasConceptScore W1966658797C185592680 @default.
• W1966658797 hasConceptScore W1966658797C192118531 @default.
• W1966658797 hasConceptScore W1966658797C195147555 @default.
• W1966658797 hasConceptScore W1966658797C20251656 @default.
• W1966658797 hasConceptScore W1966658797C204779464 @default.
• W1966658797 hasConceptScore W1966658797C2777499176 @default.
• W1966658797 hasConceptScore W1966658797C2777790778 @default.
• W1966658797 hasConceptScore W1966658797C2779826832 @default.
• W1966658797 hasConceptScore W1966658797C2780909259 @default.
• W1966658797 hasConceptScore W1966658797C55493867 @default.
• W1966658797 hasConceptScore W1966658797C62231903 @default.
• W1966658797 hasConceptScore W1966658797C71924100 @default.
• W1966658797 hasConceptScore W1966658797C86803240 @default.
• W1966658797 hasConceptScore W1966658797C9262364 @default.
• W1966658797 hasIssue "4" @default.
• W1966658797 hasLocation W19666587971 @default.
• W1966658797 hasLocation W19666587972 @default.
• W1966658797 hasOpenAccess W1966658797 @default.
• W1966658797 hasPrimaryLocation W19666587971 @default.
• W1966658797 hasRelatedWork W128851715 @default.
• W1966658797 hasRelatedWork W1490465614 @default.
• W1966658797 hasRelatedWork W1966658797 @default.
• W1966658797 hasRelatedWork W1972519976 @default.
• W1966658797 hasRelatedWork W1973103395 @default.
• W1966658797 hasRelatedWork W1979355680 @default.
• W1966658797 hasRelatedWork W2012721461 @default.
• W1966658797 hasRelatedWork W2057520203 @default.

• next