FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966668504> ?p ?o ?g. }

• W1966668504 endingPage "e98034" @default.
• W1966668504 startingPage "e98034" @default.
• W1966668504 abstract "Cancer metastasis is a complex process involving cell-cell interactions mediated by cell adhesive molecules. In this study we determine the adhesion strength between an endothelial cell monolayer and tumor cells of different metastatic potentials using Atomic Force Microscopy. We show that the rupture forces of receptor-ligand bonds increase with retraction speed and range between 20 and 70 pN. It is shown that the most invasive cell lines (T24, J82) form the strongest bonds with endothelial cells. Using ICAM-1 coated substrates and a monoclonal antibody specific for ICAM-1, we demonstrate that ICAM-1 serves as a key receptor on endothelial cells and that its interactions with ligands expressed by tumor cells are correlated with the rupture forces obtained with the most invasive cancer cells (T24, J82). For the less invasive cancer cells (RT112), endothelial ICAM-1 does not seem to play any role in the adhesion process. Moreover, a detailed analysis of the distribution of rupture forces suggests that ICAM-1 interacts preferentially with one ligand on T24 cancer cells and with two ligands on J82 cancer cells. Possible counter receptors for these interactions are CD43 and MUC1, two known ligands for ICAM-1 which are expressed by these cancer cells." @default.
• W1966668504 created "2016-06-24" @default.
• W1966668504 creator A5001693489 @default.
• W1966668504 creator A5041988740 @default.
• W1966668504 creator A5050129663 @default.
• W1966668504 creator A5089975355 @default.
• W1966668504 date "2014-05-23" @default.
• W1966668504 modified "2023-10-15" @default.
• W1966668504 title "Atomic Force Microscopy Reveals a Role for Endothelial Cell ICAM-1 Expression in Bladder Cancer Cell Adherence" @default.
• W1966668504 cites W1487498644 @default.
• W1966668504 cites W1586966961 @default.
• W1966668504 cites W1656531078 @default.
• W1966668504 cites W1658530584 @default.
• W1966668504 cites W1968472714 @default.
• W1966668504 cites W1969335454 @default.
• W1966668504 cites W1976348840 @default.
• W1966668504 cites W1983469579 @default.
• W1966668504 cites W1984870208 @default.
• W1966668504 cites W1986713431 @default.
• W1966668504 cites W1986879468 @default.
• W1966668504 cites W1989149917 @default.
• W1966668504 cites W1992320523 @default.
• W1966668504 cites W1992680151 @default.
• W1966668504 cites W1996648820 @default.
• W1966668504 cites W2005133216 @default.
• W1966668504 cites W2009404448 @default.
• W1966668504 cites W2010227280 @default.
• W1966668504 cites W2011682997 @default.
• W1966668504 cites W2012809150 @default.
• W1966668504 cites W2019877102 @default.
• W1966668504 cites W2022233074 @default.
• W1966668504 cites W2022788095 @default.
• W1966668504 cites W2025710957 @default.
• W1966668504 cites W2027854020 @default.
• W1966668504 cites W2046928174 @default.
• W1966668504 cites W2052192720 @default.
• W1966668504 cites W2059501766 @default.
• W1966668504 cites W2068318644 @default.
• W1966668504 cites W2078237256 @default.
• W1966668504 cites W2088992013 @default.
• W1966668504 cites W2099386776 @default.
• W1966668504 cites W2110569167 @default.
• W1966668504 cites W2127920357 @default.
• W1966668504 cites W2139644888 @default.
• W1966668504 cites W2155555524 @default.
• W1966668504 cites W2160064889 @default.
• W1966668504 cites W2164491927 @default.
• W1966668504 cites W4211224216 @default.
• W1966668504 cites W5035939 @default.
• W1966668504 doi "https://doi.org/10.1371/journal.pone.0098034" @default.
• W1966668504 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4032264" @default.
• W1966668504 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24857933" @default.
• W1966668504 hasPublicationYear "2014" @default.
• W1966668504 type Work @default.
• W1966668504 sameAs 1966668504 @default.
• W1966668504 citedByCount "36" @default.
• W1966668504 countsByYear W19666685042015 @default.
• W1966668504 countsByYear W19666685042016 @default.
• W1966668504 countsByYear W19666685042017 @default.
• W1966668504 countsByYear W19666685042018 @default.
• W1966668504 countsByYear W19666685042019 @default.
• W1966668504 countsByYear W19666685042020 @default.
• W1966668504 countsByYear W19666685042021 @default.
• W1966668504 countsByYear W19666685042022 @default.
• W1966668504 countsByYear W19666685042023 @default.
• W1966668504 crossrefType "journal-article" @default.
• W1966668504 hasAuthorship W1966668504A5001693489 @default.
• W1966668504 hasAuthorship W1966668504A5041988740 @default.
• W1966668504 hasAuthorship W1966668504A5050129663 @default.
• W1966668504 hasAuthorship W1966668504A5089975355 @default.
• W1966668504 hasBestOaLocation W19666685041 @default.
• W1966668504 hasConcept C121608353 @default.
• W1966668504 hasConcept C1491633281 @default.
• W1966668504 hasConcept C16224149 @default.
• W1966668504 hasConcept C170493617 @default.
• W1966668504 hasConcept C185592680 @default.
• W1966668504 hasConcept C2779013556 @default.
• W1966668504 hasConcept C502942594 @default.
• W1966668504 hasConcept C54355233 @default.
• W1966668504 hasConcept C55493867 @default.
• W1966668504 hasConcept C85789140 @default.
• W1966668504 hasConcept C86803240 @default.
• W1966668504 hasConcept C95444343 @default.
• W1966668504 hasConcept C96232424 @default.
• W1966668504 hasConceptScore W1966668504C121608353 @default.
• W1966668504 hasConceptScore W1966668504C1491633281 @default.
• W1966668504 hasConceptScore W1966668504C16224149 @default.
• W1966668504 hasConceptScore W1966668504C170493617 @default.
• W1966668504 hasConceptScore W1966668504C185592680 @default.
• W1966668504 hasConceptScore W1966668504C2779013556 @default.
• W1966668504 hasConceptScore W1966668504C502942594 @default.
• W1966668504 hasConceptScore W1966668504C54355233 @default.
• W1966668504 hasConceptScore W1966668504C55493867 @default.
• W1966668504 hasConceptScore W1966668504C85789140 @default.
• W1966668504 hasConceptScore W1966668504C86803240 @default.
• W1966668504 hasConceptScore W1966668504C95444343 @default.
• W1966668504 hasConceptScore W1966668504C96232424 @default.
• W1966668504 hasIssue "5" @default.

• next