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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966677529> ?p ?o ?g. }

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• W1966677529 startingPage "96" @default.
• W1966677529 abstract "In order to identify additional factors required for nuclear export of messenger RNA, a genetic screen was conducted with a yeast mutant deficient in a factor Gle1p, which associates with the nuclear pore complex (NPC). The three genes identified encode phospholipase C and two potential inositol polyphosphate kinases. Together, these constitute a signaling pathway from phosphatidylinositol 4, 5-bisphosphate to inositol hexakisphosphate (IP6). The common downstream effects of mutations in each component were deficiencies in IP6 synthesis and messenger RNA export, indicating a role for IP6 in GLE1 function and messenger RNA export." @default.
• W1966677529 created "2016-06-24" @default.
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• W1966677529 date "1999-07-02" @default.
• W1966677529 modified "2023-09-28" @default.
• W1966677529 title "A Phospholipase C-Dependent Inositol Polyphosphate Kinase Pathway Required for Efficient Messenger RNA Export" @default.
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• W1966677529 doi "https://doi.org/10.1126/science.285.5424.96" @default.
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