Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966681968> ?p ?o ?g. }
- W1966681968 endingPage "581" @default.
- W1966681968 startingPage "569" @default.
- W1966681968 abstract "Background: Inhibition of inappropriate tyrosine kinase activity by neoplasms is an attractive strategy for the treatment of malignancy. Objective: We aimed to produce a concise review of the potential role of hepatocyte growth factor (HGF)/Mesenchymal-epithelial transition factor (MET) tyrosine kinase pathway inhibition in the treatment of cancer. Methods: The current literature, abstracts and internet resources related to HGF/MET structure, function and inhibition are summarized. The potential of inhibiting this pathway as a therapy for cancer and remaining hurdles prior to routine clinical use of MET inhibition are discussed. Results/conclusions: Current knowledge suggests that the inhibition of the HGF/MET pathway has significant potential for the treatment of cancer. A number of MET inhibitor molecules are nearing completion of their development for clinical use." @default.
- W1966681968 created "2016-06-24" @default.
- W1966681968 creator A5021545085 @default.
- W1966681968 creator A5032632922 @default.
- W1966681968 creator A5071263980 @default.
- W1966681968 date "2009-04-27" @default.
- W1966681968 modified "2023-10-17" @default.
- W1966681968 title "Inhibition of HGF/MET as therapy for malignancy" @default.
- W1966681968 cites W1426393029 @default.
- W1966681968 cites W1586440254 @default.
- W1966681968 cites W1649526546 @default.
- W1966681968 cites W179872407 @default.
- W1966681968 cites W1846395924 @default.
- W1966681968 cites W1966843521 @default.
- W1966681968 cites W1972607682 @default.
- W1966681968 cites W1973905761 @default.
- W1966681968 cites W1973966923 @default.
- W1966681968 cites W1974487824 @default.
- W1966681968 cites W1976718703 @default.
- W1966681968 cites W1983822371 @default.
- W1966681968 cites W1985374152 @default.
- W1966681968 cites W1988936428 @default.
- W1966681968 cites W1989401198 @default.
- W1966681968 cites W1990115557 @default.
- W1966681968 cites W1994679514 @default.
- W1966681968 cites W1995377169 @default.
- W1966681968 cites W1995862211 @default.
- W1966681968 cites W1997923564 @default.
- W1966681968 cites W1998479952 @default.
- W1966681968 cites W1998799031 @default.
- W1966681968 cites W1998971866 @default.
- W1966681968 cites W1999740664 @default.
- W1966681968 cites W2002206578 @default.
- W1966681968 cites W2005042704 @default.
- W1966681968 cites W2005092992 @default.
- W1966681968 cites W2008567068 @default.
- W1966681968 cites W2012792646 @default.
- W1966681968 cites W2013678879 @default.
- W1966681968 cites W2016579969 @default.
- W1966681968 cites W2018672261 @default.
- W1966681968 cites W2019031019 @default.
- W1966681968 cites W2022527563 @default.
- W1966681968 cites W2026109211 @default.
- W1966681968 cites W2029654331 @default.
- W1966681968 cites W2029889193 @default.
- W1966681968 cites W2033974104 @default.
- W1966681968 cites W2036001925 @default.
- W1966681968 cites W2037968180 @default.
- W1966681968 cites W2038056960 @default.
- W1966681968 cites W2041705218 @default.
- W1966681968 cites W2041713021 @default.
- W1966681968 cites W2042919832 @default.
- W1966681968 cites W2051782283 @default.
- W1966681968 cites W2054042846 @default.
- W1966681968 cites W2054605144 @default.
- W1966681968 cites W2058191258 @default.
- W1966681968 cites W2059950450 @default.
- W1966681968 cites W2060525515 @default.
- W1966681968 cites W2071572077 @default.
- W1966681968 cites W2075917180 @default.
- W1966681968 cites W2078207148 @default.
- W1966681968 cites W2078576237 @default.
- W1966681968 cites W2085903671 @default.
- W1966681968 cites W2096844786 @default.
- W1966681968 cites W2101778925 @default.
- W1966681968 cites W2104800170 @default.
- W1966681968 cites W2107061457 @default.
- W1966681968 cites W2107699503 @default.
- W1966681968 cites W2115332043 @default.
- W1966681968 cites W2117164669 @default.
- W1966681968 cites W2117293305 @default.
- W1966681968 cites W2121371052 @default.
- W1966681968 cites W2121812224 @default.
- W1966681968 cites W2134659609 @default.
- W1966681968 cites W2134755472 @default.
- W1966681968 cites W2136390065 @default.
- W1966681968 cites W2138309116 @default.
- W1966681968 cites W2138896702 @default.
- W1966681968 cites W2139440398 @default.
- W1966681968 cites W2141277115 @default.
- W1966681968 cites W2150424194 @default.
- W1966681968 cites W2162014238 @default.
- W1966681968 cites W2164042520 @default.
- W1966681968 cites W2166927748 @default.
- W1966681968 cites W2328693672 @default.
- W1966681968 cites W2330176638 @default.
- W1966681968 cites W2530681482 @default.
- W1966681968 cites W4232879943 @default.
- W1966681968 cites W44016002 @default.
- W1966681968 doi "https://doi.org/10.1517/14728220902853917" @default.
- W1966681968 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19397476" @default.
- W1966681968 hasPublicationYear "2009" @default.
- W1966681968 type Work @default.
- W1966681968 sameAs 1966681968 @default.
- W1966681968 citedByCount "34" @default.
- W1966681968 countsByYear W19666819682012 @default.
- W1966681968 countsByYear W19666819682013 @default.
- W1966681968 countsByYear W19666819682014 @default.