FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966683952> ?p ?o ?g. }

• W1966683952 endingPage "1373" @default.
• W1966683952 startingPage "1362" @default.
• W1966683952 abstract "Serotonin (5-HT) is well known to affect the motivational properties of stimuli predictive of rewards as well as the inhibitory control of behavior. Here, central 5-HT depletion was induced by the acute tryptophan (TRP) depletion (ATD) procedure in young healthy volunteers to examine the role of 5-HT in motivated action and prepotent response inhibition. A novel reaction-time task, tailored to individual differences in general cognitive speed, was employed to measure the guidance of behavior by motivationally relevant signals predictive of reinforcement likelihood, while the stop-signal reaction-time task was used to measure response inhibition. Following the TRP-balancing control drink, cues predictive of high-reinforcement certainty induced faster, but less accurate responses compared with cues predictive of lower reinforcement certainty. Depletion of central 5-HT modulated this coupling between motivation and action by slowing responses and increasing accuracy as a function of incentive certainty. These effects of ATD on motivated action correlated highly with individual differences in the personality trait of Nonplanning Impulsiveness (Barratt Impulsivity Scale (BIS-11)), so that strongest effects on motivated action were observed in high-impulsive individuals. By contrast, ATD left unaltered the ability to inhibit prepotent responses. Our findings may have implications for a variety of neuropsychiatric disorders including impulsive aggressive disorders and depression." @default.
• W1966683952 created "2016-06-24" @default.
• W1966683952 creator A5003784928 @default.
• W1966683952 creator A5020886846 @default.
• W1966683952 creator A5023147804 @default.
• W1966683952 creator A5027457588 @default.
• W1966683952 creator A5060063783 @default.
• W1966683952 creator A5072571980 @default.
• W1966683952 date "2005-03-16" @default.
• W1966683952 modified "2023-10-16" @default.
• W1966683952 title "Tryptophan Depletion Disrupts the Motivational Guidance of Goal-Directed Behavior as a Function of Trait Impulsivity" @default.
• W1966683952 cites W1481546376 @default.
• W1966683952 cites W1969275478 @default.
• W1966683952 cites W1976487565 @default.
• W1966683952 cites W1977947329 @default.
• W1966683952 cites W1978443369 @default.
• W1966683952 cites W1978477505 @default.
• W1966683952 cites W1983684123 @default.
• W1966683952 cites W1984470666 @default.
• W1966683952 cites W1987515587 @default.
• W1966683952 cites W1991060469 @default.
• W1966683952 cites W1991271750 @default.
• W1966683952 cites W1992149782 @default.
• W1966683952 cites W1992968336 @default.
• W1966683952 cites W1994561821 @default.
• W1966683952 cites W1994843226 @default.
• W1966683952 cites W1996084072 @default.
• W1966683952 cites W2005898154 @default.
• W1966683952 cites W2006068076 @default.
• W1966683952 cites W2010687330 @default.
• W1966683952 cites W2015827110 @default.
• W1966683952 cites W2017881207 @default.
• W1966683952 cites W2019663609 @default.
• W1966683952 cites W2020020413 @default.
• W1966683952 cites W2029111326 @default.
• W1966683952 cites W2033123455 @default.
• W1966683952 cites W2033405588 @default.
• W1966683952 cites W2047789431 @default.
• W1966683952 cites W2051068515 @default.
• W1966683952 cites W2054310646 @default.
• W1966683952 cites W2054515032 @default.
• W1966683952 cites W2059208609 @default.
• W1966683952 cites W2063816280 @default.
• W1966683952 cites W2067012376 @default.
• W1966683952 cites W2069947117 @default.
• W1966683952 cites W2071359470 @default.
• W1966683952 cites W2071510125 @default.
• W1966683952 cites W2072646528 @default.
• W1966683952 cites W2073158960 @default.
• W1966683952 cites W2079308535 @default.
• W1966683952 cites W2082554730 @default.
• W1966683952 cites W2087856744 @default.
• W1966683952 cites W2089314671 @default.
• W1966683952 cites W2093976895 @default.
• W1966683952 cites W2094026124 @default.
• W1966683952 cites W2094976308 @default.
• W1966683952 cites W2095331684 @default.
• W1966683952 cites W2095629588 @default.
• W1966683952 cites W2099880858 @default.
• W1966683952 cites W2116892542 @default.
• W1966683952 cites W2147639837 @default.
• W1966683952 cites W2154118084 @default.
• W1966683952 cites W2167740558 @default.
• W1966683952 cites W2294684135 @default.
• W1966683952 cites W4213265599 @default.
• W1966683952 cites W4234892436 @default.
• W1966683952 cites W4238789802 @default.
• W1966683952 doi "https://doi.org/10.1038/sj.npp.1300704" @default.
• W1966683952 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15770237" @default.
• W1966683952 hasPublicationYear "2005" @default.
• W1966683952 type Work @default.
• W1966683952 sameAs 1966683952 @default.
• W1966683952 citedByCount "133" @default.
• W1966683952 countsByYear W19666839522012 @default.
• W1966683952 countsByYear W19666839522013 @default.
• W1966683952 countsByYear W19666839522014 @default.
• W1966683952 countsByYear W19666839522015 @default.
• W1966683952 countsByYear W19666839522016 @default.
• W1966683952 countsByYear W19666839522017 @default.
• W1966683952 countsByYear W19666839522018 @default.
• W1966683952 countsByYear W19666839522019 @default.
• W1966683952 countsByYear W19666839522020 @default.
• W1966683952 countsByYear W19666839522021 @default.
• W1966683952 countsByYear W19666839522022 @default.
• W1966683952 countsByYear W19666839522023 @default.
• W1966683952 crossrefType "journal-article" @default.
• W1966683952 hasAuthorship W1966683952A5003784928 @default.
• W1966683952 hasAuthorship W1966683952A5020886846 @default.
• W1966683952 hasAuthorship W1966683952A5023147804 @default.
• W1966683952 hasAuthorship W1966683952A5027457588 @default.
• W1966683952 hasAuthorship W1966683952A5060063783 @default.
• W1966683952 hasAuthorship W1966683952A5072571980 @default.
• W1966683952 hasBestOaLocation W19666839521 @default.
• W1966683952 hasConcept C106934330 @default.
• W1966683952 hasConcept C121332964 @default.
• W1966683952 hasConcept C138496976 @default.
• W1966683952 hasConcept C148374829 @default.
• W1966683952 hasConcept C15744967 @default.

• next