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- W1966686046 abstract "Deciphering the roles and structure-activity relationships of carbohydrates in biological processes requires access to sugar molecules of confirmed structure and high purity. Chemical synthesis is one of the best ways to obtain such access. However, the synthesis of carbohydrates has long been impeded by two major challenges--the regioselective protection of the polyol moiety of each monosaccharide building block and the stereoselective glycosylation to produce oligosaccharides of desired length. Here, we review the development of the first regioselective protection-glycosylation and a revolutionary regioselective combinatorial one-pot protection of monosaccharides that can be used to differentiate the various hydroxy groups of monosaccharides with a vast array of orthogonal protective groups in one-pot procedures." @default.
- W1966686046 created "2016-06-24" @default.
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- W1966686046 date "2011-09-08" @default.
- W1966686046 modified "2023-09-25" @default.
- W1966686046 title "ChemInform Abstract: Regioselective One-Pot Protection and Protection-Glycosylation of Carbohydrates" @default.
- W1966686046 cites W2949243584 @default.
- W1966686046 doi "https://doi.org/10.1002/chin.201140231" @default.
- W1966686046 hasPublicationYear "2011" @default.
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