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• W1966687552 endingPage "1422" @default.
• W1966687552 startingPage "1415" @default.
• W1966687552 abstract "The main objective of this study was to assess in 5-6-year-old French children (n=234) the persistence of antibodies induced by a primary series vaccination (at 2-4 months of age) and a first booster (at 12-16 months of age) with a pentavalent two-component acellular pertussis combined vaccine (DTacP-IPV-Hib; Pentavac). The second objective was to evaluate in these 5-6-year-old French children the safety and the immunogenicity of a tetravalent acellular pertussis combined vaccine (DTacP-IPV; Tetravac) given as second booster.Seroprotective antibody levels against diphtheria, tetanus, types 1-3 poliomyelitis and PRP were maintained 4-5 years after primary-vaccination and first booster with Pentavac. As expected, anti-PT antibodies levels were low, suggesting that children were not colonised by Bordetella pertussis. The second booster with Tetravac was well tolerated and elicited a strong booster response for all antigens.acellular pertussis combined vaccine, used in primary-vaccination, could be considered as having the same priming effect and the same efficacy as whole cell pertussis vaccine." @default.
• W1966687552 created "2016-06-24" @default.
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• W1966687552 date "2004-03-01" @default.
• W1966687552 modified "2023-09-27" @default.
• W1966687552 title "Antibody persistence against diphtheria, tetanus, pertussis, poliomyelitis and Haemophilus influenzae type b (Hib) in 5–6-year-old children after primary vaccination and first booster with a pentavalent combined acellular pertussis vaccine: immunogenicity and tolerance of a tetravalent combined acellular pertussis vaccine given as a second booster" @default.
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• W1966687552 doi "https://doi.org/10.1016/j.vaccine.2003.10.025" @default.
• W1966687552 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15063564" @default.
• W1966687552 hasPublicationYear "2004" @default.
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