FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966706659> ?p ?o ?g. }

• W1966706659 endingPage "247" @default.
• W1966706659 startingPage "241" @default.
• W1966706659 abstract "Several cell types have been shown to produce type I interferons (IFN). Of human leukocytes, monocytes and especially type 2 dendritic cell precursors (pDC2) seem to be the main producers and also have a wide spectrum of cytokine production. However, neutrophils seem to have a limited capacity for cytokine production but possess efficient defense mechanisms vs. bacterial infection by phagocytosis and degranulation. To determine whether they also have antiviral functions, IFN-alpha and IFN-beta were measured in preparations of pure neutrophils. The capacity of neutrophils to produce type I IFN is controversial. Additionally, macrophage inflammatory protein-1alpha (MIP-1alpha) and MIP-1beta were measured, as they are described to have indirect or direct antiviral activity. As stimulants, active and inactivated Newcastle disease virus (NDV), Sendai virus, and granulocyte colony-stimulating factor (G-CSF) were used. Peripheral blood mononuclear cells (PBMC) from the same donors were highly reactive to viral stimulation, whereas neutrophils failed to produce IFN but produced MIP-1beta in response to NDV. We conclude that neutrophils fail to prevent viral infection by IFN production but probably possess alternative mechanisms, such as secreting MIP-1beta in response to viruses." @default.
• W1966706659 created "2016-06-24" @default.
• W1966706659 creator A5014418918 @default.
• W1966706659 creator A5019804606 @default.
• W1966706659 creator A5026925145 @default.
• W1966706659 creator A5050192465 @default.
• W1966706659 date "2001-04-01" @default.
• W1966706659 modified "2023-09-23" @default.
• W1966706659 title "Human Neutrophils Produce Macrophage Inhibitory Protein-1β but Not Type I Interferons in Response to Viral Stimulation" @default.
• W1966706659 cites W110724120 @default.
• W1966706659 cites W1409275497 @default.
• W1966706659 cites W1607189030 @default.
• W1966706659 cites W1633583339 @default.
• W1966706659 cites W1916213760 @default.
• W1966706659 cites W1985723826 @default.
• W1966706659 cites W2006772331 @default.
• W1966706659 cites W2011402738 @default.
• W1966706659 cites W2042537047 @default.
• W1966706659 cites W2043966220 @default.
• W1966706659 cites W2050431219 @default.
• W1966706659 cites W2075836508 @default.
• W1966706659 cites W2113710519 @default.
• W1966706659 cites W2119834166 @default.
• W1966706659 cites W2130703653 @default.
• W1966706659 cites W2159861052 @default.
• W1966706659 cites W2293885897 @default.
• W1966706659 cites W2318003275 @default.
• W1966706659 cites W4313376938 @default.
• W1966706659 doi "https://doi.org/10.1089/107999001750169899" @default.
• W1966706659 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11359655" @default.
• W1966706659 hasPublicationYear "2001" @default.
• W1966706659 type Work @default.
• W1966706659 sameAs 1966706659 @default.
• W1966706659 citedByCount "14" @default.
• W1966706659 countsByYear W19667066592012 @default.
• W1966706659 countsByYear W19667066592013 @default.
• W1966706659 countsByYear W19667066592014 @default.
• W1966706659 countsByYear W19667066592015 @default.
• W1966706659 countsByYear W19667066592019 @default.
• W1966706659 crossrefType "journal-article" @default.
• W1966706659 hasAuthorship W1966706659A5014418918 @default.
• W1966706659 hasAuthorship W1966706659A5019804606 @default.
• W1966706659 hasAuthorship W1966706659A5026925145 @default.
• W1966706659 hasAuthorship W1966706659A5050192465 @default.
• W1966706659 hasConcept C137061746 @default.
• W1966706659 hasConcept C159047783 @default.
• W1966706659 hasConcept C160448771 @default.
• W1966706659 hasConcept C169760540 @default.
• W1966706659 hasConcept C170217031 @default.
• W1966706659 hasConcept C170493617 @default.
• W1966706659 hasConcept C202751555 @default.
• W1966706659 hasConcept C203014093 @default.
• W1966706659 hasConcept C24998067 @default.
• W1966706659 hasConcept C2522874641 @default.
• W1966706659 hasConcept C2776178377 @default.
• W1966706659 hasConcept C2777478134 @default.
• W1966706659 hasConcept C2777983669 @default.
• W1966706659 hasConcept C2778690821 @default.
• W1966706659 hasConcept C2779244956 @default.
• W1966706659 hasConcept C2780127873 @default.
• W1966706659 hasConcept C49802076 @default.
• W1966706659 hasConcept C55493867 @default.
• W1966706659 hasConcept C74172505 @default.
• W1966706659 hasConcept C86803240 @default.
• W1966706659 hasConcept C89423630 @default.
• W1966706659 hasConceptScore W1966706659C137061746 @default.
• W1966706659 hasConceptScore W1966706659C159047783 @default.
• W1966706659 hasConceptScore W1966706659C160448771 @default.
• W1966706659 hasConceptScore W1966706659C169760540 @default.
• W1966706659 hasConceptScore W1966706659C170217031 @default.
• W1966706659 hasConceptScore W1966706659C170493617 @default.
• W1966706659 hasConceptScore W1966706659C202751555 @default.
• W1966706659 hasConceptScore W1966706659C203014093 @default.
• W1966706659 hasConceptScore W1966706659C24998067 @default.
• W1966706659 hasConceptScore W1966706659C2522874641 @default.
• W1966706659 hasConceptScore W1966706659C2776178377 @default.
• W1966706659 hasConceptScore W1966706659C2777478134 @default.
• W1966706659 hasConceptScore W1966706659C2777983669 @default.
• W1966706659 hasConceptScore W1966706659C2778690821 @default.
• W1966706659 hasConceptScore W1966706659C2779244956 @default.
• W1966706659 hasConceptScore W1966706659C2780127873 @default.
• W1966706659 hasConceptScore W1966706659C49802076 @default.
• W1966706659 hasConceptScore W1966706659C55493867 @default.
• W1966706659 hasConceptScore W1966706659C74172505 @default.
• W1966706659 hasConceptScore W1966706659C86803240 @default.
• W1966706659 hasConceptScore W1966706659C89423630 @default.
• W1966706659 hasIssue "4" @default.
• W1966706659 hasLocation W19667066591 @default.
• W1966706659 hasLocation W19667066592 @default.
• W1966706659 hasOpenAccess W1966706659 @default.
• W1966706659 hasPrimaryLocation W19667066591 @default.
• W1966706659 hasRelatedWork W1025521678 @default.
• W1966706659 hasRelatedWork W1971747674 @default.
• W1966706659 hasRelatedWork W2010825098 @default.
• W1966706659 hasRelatedWork W2026521386 @default.
• W1966706659 hasRelatedWork W2031356164 @default.
• W1966706659 hasRelatedWork W2039512510 @default.
• W1966706659 hasRelatedWork W2113243517 @default.

• next