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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966730457> ?p ?o ?g. }

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• W1966730457 abstract "Benzo[a]pyrene (B[a]P) and its 7,8-dihydrodiol form were metabolically activated to malignantly transform a non-tumorigenic rat tracheal epithelial cell line in culture. The proximal carcinogenic metabolite of B[a]P, diolepoxide I, was more efficient in transforming the epithelial cell line than the intermediate or parent compound, even at a 50- or 100-fold lower concentration, respectively. Inoculations of the transformed cell lines into immunosuppressed isogenic recipients produced differentiated carcinomas similar to those which occur in humans." @default.
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• W1966730457 date "1980-02-01" @default.
• W1966730457 modified "2023-09-23" @default.
• W1966730457 title "Transformation of rat tracheal epithelial cells by benzo[a]pyrene and its metabolites" @default.
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• W1966730457 doi "https://doi.org/10.1016/0304-3835(80)90144-5" @default.
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