FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966742243> ?p ?o ?g. }

• W1966742243 endingPage "403" @default.
• W1966742243 startingPage "400" @default.
• W1966742243 abstract "We describe two patients with haemolytic uraemic syndrome (HUS) associated with invasive Streptococcus pneumoniae infection. Both patients had transiently reduced serum concentrations of complement C3. One had reduced expression of CD46 and never recovered renal function. No constitutive defect in regulation of the alternative pathway of complement activation was demonstrated in the second patient but there was an apparent improvement in her condition after administration of eculizumab. The most widely accepted mechanism for pneumococcal HUS is endothelial cell damage by pre-formed antibodies against the Thomsen-Friedenreich antigen. This explanation does not bear rigorous scrutiny. We postulate that transiently dysregulated complement activation may play a role in the pathogenesis of pneumococcal disease. We further postulate that the mechanism could be enhanced binding of factor H to the neuraminidase-altered surface of endothelial cells or reduced binding of factor H to the endothelial cell surface mediated by competitive binding of factor H by pneumococcal surface protein C (pspC)." @default.
• W1966742243 created "2016-06-24" @default.
• W1966742243 creator A5003476850 @default.
• W1966742243 creator A5031315059 @default.
• W1966742243 creator A5062400044 @default.
• W1966742243 date "2013-09-01" @default.
• W1966742243 modified "2023-10-16" @default.
• W1966742243 title "Does dysregulated complement activation contribute to haemolytic uraemic syndrome secondary to Streptococcus pneumoniae?" @default.
• W1966742243 cites W1568556261 @default.
• W1966742243 cites W1964028055 @default.
• W1966742243 cites W1966941198 @default.
• W1966742243 cites W1981598780 @default.
• W1966742243 cites W1992721882 @default.
• W1966742243 cites W1995507184 @default.
• W1966742243 cites W1995652472 @default.
• W1966742243 cites W2016660261 @default.
• W1966742243 cites W2031360287 @default.
• W1966742243 cites W2031628865 @default.
• W1966742243 cites W2036694775 @default.
• W1966742243 cites W2037817455 @default.
• W1966742243 cites W2042777883 @default.
• W1966742243 cites W2059727759 @default.
• W1966742243 cites W2074286693 @default.
• W1966742243 cites W2078820067 @default.
• W1966742243 cites W2080527440 @default.
• W1966742243 cites W2092886851 @default.
• W1966742243 cites W2098315002 @default.
• W1966742243 cites W2118003105 @default.
• W1966742243 cites W2123238891 @default.
• W1966742243 cites W2145362615 @default.
• W1966742243 cites W2150041016 @default.
• W1966742243 cites W2155989698 @default.
• W1966742243 cites W2158943356 @default.
• W1966742243 cites W2164395407 @default.
• W1966742243 cites W2167866530 @default.
• W1966742243 doi "https://doi.org/10.1016/j.mehy.2013.05.030" @default.
• W1966742243 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23786906" @default.
• W1966742243 hasPublicationYear "2013" @default.
• W1966742243 type Work @default.
• W1966742243 sameAs 1966742243 @default.
• W1966742243 citedByCount "37" @default.
• W1966742243 countsByYear W19667422432014 @default.
• W1966742243 countsByYear W19667422432015 @default.
• W1966742243 countsByYear W19667422432016 @default.
• W1966742243 countsByYear W19667422432017 @default.
• W1966742243 countsByYear W19667422432018 @default.
• W1966742243 countsByYear W19667422432019 @default.
• W1966742243 countsByYear W19667422432020 @default.
• W1966742243 countsByYear W19667422432021 @default.
• W1966742243 countsByYear W19667422432022 @default.
• W1966742243 countsByYear W19667422432023 @default.
• W1966742243 crossrefType "journal-article" @default.
• W1966742243 hasAuthorship W1966742243A5003476850 @default.
• W1966742243 hasAuthorship W1966742243A5031315059 @default.
• W1966742243 hasAuthorship W1966742243A5062400044 @default.
• W1966742243 hasConcept C111684460 @default.
• W1966742243 hasConcept C159654299 @default.
• W1966742243 hasConcept C171279029 @default.
• W1966742243 hasConcept C189446657 @default.
• W1966742243 hasConcept C203014093 @default.
• W1966742243 hasConcept C2777637130 @default.
• W1966742243 hasConcept C2777991916 @default.
• W1966742243 hasConcept C2780942790 @default.
• W1966742243 hasConcept C2781253189 @default.
• W1966742243 hasConcept C501593827 @default.
• W1966742243 hasConcept C86803240 @default.
• W1966742243 hasConcept C89423630 @default.
• W1966742243 hasConceptScore W1966742243C111684460 @default.
• W1966742243 hasConceptScore W1966742243C159654299 @default.
• W1966742243 hasConceptScore W1966742243C171279029 @default.
• W1966742243 hasConceptScore W1966742243C189446657 @default.
• W1966742243 hasConceptScore W1966742243C203014093 @default.
• W1966742243 hasConceptScore W1966742243C2777637130 @default.
• W1966742243 hasConceptScore W1966742243C2777991916 @default.
• W1966742243 hasConceptScore W1966742243C2780942790 @default.
• W1966742243 hasConceptScore W1966742243C2781253189 @default.
• W1966742243 hasConceptScore W1966742243C501593827 @default.
• W1966742243 hasConceptScore W1966742243C86803240 @default.
• W1966742243 hasConceptScore W1966742243C89423630 @default.
• W1966742243 hasIssue "3" @default.
• W1966742243 hasLocation W19667422431 @default.
• W1966742243 hasLocation W19667422432 @default.
• W1966742243 hasOpenAccess W1966742243 @default.
• W1966742243 hasPrimaryLocation W19667422431 @default.
• W1966742243 hasRelatedWork W2021691030 @default.
• W1966742243 hasRelatedWork W2110518735 @default.
• W1966742243 hasRelatedWork W2130269036 @default.
• W1966742243 hasRelatedWork W2135754582 @default.
• W1966742243 hasRelatedWork W2751170277 @default.
• W1966742243 hasRelatedWork W2979743379 @default.
• W1966742243 hasRelatedWork W3016222789 @default.
• W1966742243 hasRelatedWork W3080563564 @default.
• W1966742243 hasRelatedWork W4285137799 @default.
• W1966742243 hasRelatedWork W4321132768 @default.
• W1966742243 hasVolume "81" @default.
• W1966742243 isParatext "false" @default.
• W1966742243 isRetracted "false" @default.
• W1966742243 magId "1966742243" @default.

• next