FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966746720> ?p ?o ?g. }

• W1966746720 endingPage "1115" @default.
• W1966746720 startingPage "1109" @default.
• W1966746720 abstract "Twenty-seven prepubertal boys and 9 prepubertal girls with constitutionally delayed growth were treated with the anabolic steroid oxandrolone for 12 months and followed until they reached final height. Sixteen boys were treated with a mean dose of 0.12 mg/kg.day [low dose (LD)] and 11 boys with a mean dose of 0.22 mg/kg.day [high dose (HD)]. The girls were treated with a mean dose of 0.1 mg/kg.day. Thirteen boys and 9 girls served as controls. On oxandrolone the mean height velocity increased from 4.0 to 8.6 (boys, LD), from 4.3 to 8.9 (boys, HD), and from 4.3 to 8.3 cm/yr (girls). The immediate posttreatment height velocity was significantly higher than the pretreatment height velocity (P less than 0.05), regardless of whether the patients had entered puberty. On oxandrolone the mean ratios of change in bone age/change in chronological age were 2.0 (boys, LD), 2.3 (boys, HD), and 2.0 yr/yr (girls) and continued to be accelerated during the 6 months after treatment. Height predictions at the onset of treatment and after 6 months off treatment were calculated by three different methods: Bayley-Pinneau (BP), Roche-Wainer-Thissen (RWT), and Tanner Mark II (T II). In the boys (LD) mean height predictions increased significantly by the methods of BP (3.3 cm) and RWT (2.9 cm), but not by the method of T II (0.6 cm). In the boys (HD) no significant change in height predictions was noted. In the girls mean height predictions remained unchanged by BP and RWT, but decreased significantly by T II (-2.5 cm). The difference between final height and initial height prediction was taken as a measure of the influence of the treatment on adult height. In all three treatment groups the difference between final height and initial height prediction, calculated with all three methods, did not differ from the control group. We conclude that oxandrolone treatment for 1 yr has no effect on adult height. In spite of this, the use of an anabolic steroid such as oxandrolone may still have value, as an increase in height velocity and an earlier onset of puberty may benefit short children suffering from psychological problems due to delay of growth and development." @default.
• W1966746720 created "2016-06-24" @default.
• W1966746720 creator A5047091966 @default.
• W1966746720 creator A5077590387 @default.
• W1966746720 creator A5082664018 @default.
• W1966746720 date "1989-12-01" @default.
• W1966746720 modified "2023-09-27" @default.
• W1966746720 title "Oxandrolone in Constitutionally Delayed Growth, a Longitudinal Study up to Final Height*" @default.
• W1966746720 cites W1485539556 @default.
• W1966746720 cites W1969264208 @default.
• W1966746720 cites W1983964129 @default.
• W1966746720 cites W1987043074 @default.
• W1966746720 cites W1989831107 @default.
• W1966746720 cites W1997536463 @default.
• W1966746720 cites W2009158296 @default.
• W1966746720 cites W2019499634 @default.
• W1966746720 cites W2024674492 @default.
• W1966746720 cites W2028197744 @default.
• W1966746720 cites W2031439543 @default.
• W1966746720 cites W2036993026 @default.
• W1966746720 cites W2048370865 @default.
• W1966746720 cites W2054507846 @default.
• W1966746720 cites W2061494877 @default.
• W1966746720 cites W2067481571 @default.
• W1966746720 cites W2068581136 @default.
• W1966746720 cites W2072483071 @default.
• W1966746720 cites W2081026045 @default.
• W1966746720 cites W2312979549 @default.
• W1966746720 cites W2337115855 @default.
• W1966746720 cites W2411426985 @default.
• W1966746720 cites W2468438026 @default.
• W1966746720 cites W2801693001 @default.
• W1966746720 doi "https://doi.org/10.1210/jcem-69-6-1109" @default.
• W1966746720 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2584350" @default.
• W1966746720 hasPublicationYear "1989" @default.
• W1966746720 type Work @default.
• W1966746720 sameAs 1966746720 @default.
• W1966746720 citedByCount "44" @default.
• W1966746720 countsByYear W19667467202012 @default.
• W1966746720 countsByYear W19667467202015 @default.
• W1966746720 countsByYear W19667467202016 @default.
• W1966746720 countsByYear W19667467202019 @default.
• W1966746720 countsByYear W19667467202021 @default.
• W1966746720 countsByYear W19667467202023 @default.
• W1966746720 crossrefType "journal-article" @default.
• W1966746720 hasAuthorship W1966746720A5047091966 @default.
• W1966746720 hasAuthorship W1966746720A5077590387 @default.
• W1966746720 hasAuthorship W1966746720A5082664018 @default.
• W1966746720 hasBestOaLocation W19667467201 @default.
• W1966746720 hasConcept C1008401 @default.
• W1966746720 hasConcept C126322002 @default.
• W1966746720 hasConcept C134018914 @default.
• W1966746720 hasConcept C2779390809 @default.
• W1966746720 hasConcept C2779733885 @default.
• W1966746720 hasConcept C2910820727 @default.
• W1966746720 hasConcept C2984496839 @default.
• W1966746720 hasConcept C71315377 @default.
• W1966746720 hasConcept C71924100 @default.
• W1966746720 hasConcept C89551170 @default.
• W1966746720 hasConceptScore W1966746720C1008401 @default.
• W1966746720 hasConceptScore W1966746720C126322002 @default.
• W1966746720 hasConceptScore W1966746720C134018914 @default.
• W1966746720 hasConceptScore W1966746720C2779390809 @default.
• W1966746720 hasConceptScore W1966746720C2779733885 @default.
• W1966746720 hasConceptScore W1966746720C2910820727 @default.
• W1966746720 hasConceptScore W1966746720C2984496839 @default.
• W1966746720 hasConceptScore W1966746720C71315377 @default.
• W1966746720 hasConceptScore W1966746720C71924100 @default.
• W1966746720 hasConceptScore W1966746720C89551170 @default.
• W1966746720 hasIssue "6" @default.
• W1966746720 hasLocation W19667467201 @default.
• W1966746720 hasLocation W19667467202 @default.
• W1966746720 hasOpenAccess W1966746720 @default.
• W1966746720 hasPrimaryLocation W19667467201 @default.
• W1966746720 hasRelatedWork W1485539556 @default.
• W1966746720 hasRelatedWork W1997893596 @default.
• W1966746720 hasRelatedWork W2008093819 @default.
• W1966746720 hasRelatedWork W2037670419 @default.
• W1966746720 hasRelatedWork W2044321434 @default.
• W1966746720 hasRelatedWork W2110565742 @default.
• W1966746720 hasRelatedWork W2150978053 @default.
• W1966746720 hasRelatedWork W2337115855 @default.
• W1966746720 hasRelatedWork W3094231005 @default.
• W1966746720 hasRelatedWork W2317900737 @default.
• W1966746720 hasVolume "69" @default.
• W1966746720 isParatext "false" @default.
• W1966746720 isRetracted "false" @default.
• W1966746720 magId "1966746720" @default.
• W1966746720 workType "article" @default.