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• W1966752796 abstract "To the Editor: I read with considerable interest the article by Konstam et al (Chest 1984; 86:681–87) purporting to show the accuracy of Technitium-99m gated blood pool imaging for the measurement of right ventricular ejection fraction (RVEF). A study of similar intent was performed by our group with markedly dissimilar findings.1Hooper W Horn M Moser K Right ventricular size and function: the discrepancy between cardiac blood pool imaging techniques.Cath Cardiovasc Diag. 1982; 8: 597-606Crossref PubMed Scopus (7) Google Scholar We independently performed biplane right ventricular cineangiograms as well as 99mTc gated radionuclide studies in 14 patients. The radionuclide RVEFs were calculated using four different processing methods similar to those in the Konstam study. The angiographic determinations of RVEF were done using Ferlinz’ rule.2Ferlinz J Gorlin R Cohn P Hermann M Right ventricular volume in man.Circulation. 1974; 52: 608Crossref Scopus (147) Google Scholar Our study revealed marked variation in RVEF using different processing protocols as well as poor correlation with RVEF measured from the biplane angiograms (the r-values for the four techniques ranged from 0.23 to 0.74). We concluded that gated pool imaging of the RV using 99mTc was too inaccurate to be used in individual subjects. I suspect that Dr. Konstam's excellent correlations stem from the method used in processing the data. In our study, the RVEF was calculated from the angiograms independently and blindly from the radionuclide RVEFs. In the study by Konstam et al, this does not seem to have been the case. As anyone who has used a computer light pen or joystick to draw right ventricular regions of interest can attest, it is very easy to consciously (or subconsciously) be a little generous in one frame or a little stingy in another, especially if the operator knows what the RVEF is supposed to be from having done the first pass measurement Unless the first pass and equilibrium RVEF measurements were done independently, one must question the validity of the reported findings. Based on our study and experience, we remain skeptical about the accuracy of 99mTc gated blood pool RVEF determinations." @default.
• W1966752796 created "2016-06-24" @default.
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• W1966752796 date "1985-08-01" @default.
• W1966752796 modified "2023-09-24" @default.
• W1966752796 title "Accuracy of 99mTc Gated Blood Pool Imaging" @default.
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• W1966752796 doi "https://doi.org/10.1378/chest.88.2.315b" @default.
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