Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966787673> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W1966787673 endingPage "1486" @default.
- W1966787673 startingPage "1481" @default.
- W1966787673 abstract "The selAB operon codes for the proteins selenocysteine synthase and SELB which catalyse the synthesis and co-translational insertion of selenocysteine into protein. This communication deals with the biochemical characterisation of these proteins and in particular with their specific interaction with the selenocysteine-incorporating tRNASec. Selenocysteine synthase catalyses the synthesis of selenocysteyl-tRNASec from seryl-tRNASec in a pyridoxal phosphate-dependent reaction mechanism. The enzyme specifically recognizes the tRNASec molecule; a cooperative interaction between the tRNA binding site and the catalytically active pyridoxal phosphate site is suggested. SELB is an EF-Tu-like protein which specifically complexes selenocysteyl-tRNASec. Interaction with the selenol group of the side chain of the aminoacylated residue is a prerequisite for the formation of a stable SELB·tRNA complex. Mechanistically, this provides the biochemical basis for the exclusive selection of selenocysteyl-tRNASec in the decoding step of a selenocysteine-specific UGA triplet." @default.
- W1966787673 created "2016-06-24" @default.
- W1966787673 creator A5031863434 @default.
- W1966787673 creator A5048175299 @default.
- W1966787673 creator A5075171211 @default.
- W1966787673 date "1991-12-01" @default.
- W1966787673 modified "2023-09-27" @default.
- W1966787673 title "The function of selenocysteine synthase and SELB in the synthesis and incorporation of selenocysteine" @default.
- W1966787673 cites W1481775159 @default.
- W1966787673 cites W1486135496 @default.
- W1966787673 cites W1499041920 @default.
- W1966787673 cites W1507184493 @default.
- W1966787673 cites W1548949601 @default.
- W1966787673 cites W1558516755 @default.
- W1966787673 cites W1589576710 @default.
- W1966787673 cites W1610318839 @default.
- W1966787673 cites W2047648020 @default.
- W1966787673 cites W2054000323 @default.
- W1966787673 cites W2057683951 @default.
- W1966787673 cites W2081645231 @default.
- W1966787673 cites W2100837269 @default.
- W1966787673 cites W2168912171 @default.
- W1966787673 cites W4241213872 @default.
- W1966787673 doi "https://doi.org/10.1016/0300-9084(91)90181-y" @default.
- W1966787673 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1839607" @default.
- W1966787673 hasPublicationYear "1991" @default.
- W1966787673 type Work @default.
- W1966787673 sameAs 1966787673 @default.
- W1966787673 citedByCount "46" @default.
- W1966787673 countsByYear W19667876732013 @default.
- W1966787673 countsByYear W19667876732014 @default.
- W1966787673 countsByYear W19667876732015 @default.
- W1966787673 countsByYear W19667876732016 @default.
- W1966787673 countsByYear W19667876732017 @default.
- W1966787673 countsByYear W19667876732018 @default.
- W1966787673 countsByYear W19667876732019 @default.
- W1966787673 countsByYear W19667876732020 @default.
- W1966787673 countsByYear W19667876732022 @default.
- W1966787673 crossrefType "journal-article" @default.
- W1966787673 hasAuthorship W1966787673A5031863434 @default.
- W1966787673 hasAuthorship W1966787673A5048175299 @default.
- W1966787673 hasAuthorship W1966787673A5075171211 @default.
- W1966787673 hasConcept C104317684 @default.
- W1966787673 hasConcept C153957851 @default.
- W1966787673 hasConcept C181199279 @default.
- W1966787673 hasConcept C185592680 @default.
- W1966787673 hasConcept C2776087148 @default.
- W1966787673 hasConcept C2776376580 @default.
- W1966787673 hasConcept C2776841403 @default.
- W1966787673 hasConcept C2778760513 @default.
- W1966787673 hasConcept C2779201268 @default.
- W1966787673 hasConcept C2780859938 @default.
- W1966787673 hasConcept C538909803 @default.
- W1966787673 hasConcept C55493867 @default.
- W1966787673 hasConcept C67705224 @default.
- W1966787673 hasConcept C86803240 @default.
- W1966787673 hasConceptScore W1966787673C104317684 @default.
- W1966787673 hasConceptScore W1966787673C153957851 @default.
- W1966787673 hasConceptScore W1966787673C181199279 @default.
- W1966787673 hasConceptScore W1966787673C185592680 @default.
- W1966787673 hasConceptScore W1966787673C2776087148 @default.
- W1966787673 hasConceptScore W1966787673C2776376580 @default.
- W1966787673 hasConceptScore W1966787673C2776841403 @default.
- W1966787673 hasConceptScore W1966787673C2778760513 @default.
- W1966787673 hasConceptScore W1966787673C2779201268 @default.
- W1966787673 hasConceptScore W1966787673C2780859938 @default.
- W1966787673 hasConceptScore W1966787673C538909803 @default.
- W1966787673 hasConceptScore W1966787673C55493867 @default.
- W1966787673 hasConceptScore W1966787673C67705224 @default.
- W1966787673 hasConceptScore W1966787673C86803240 @default.
- W1966787673 hasIssue "12" @default.
- W1966787673 hasLocation W19667876731 @default.
- W1966787673 hasLocation W19667876732 @default.
- W1966787673 hasOpenAccess W1966787673 @default.
- W1966787673 hasPrimaryLocation W19667876731 @default.
- W1966787673 hasRelatedWork W1983899206 @default.
- W1966787673 hasRelatedWork W1995471774 @default.
- W1966787673 hasRelatedWork W2121336240 @default.
- W1966787673 hasRelatedWork W2141386840 @default.
- W1966787673 hasRelatedWork W2172132891 @default.
- W1966787673 hasRelatedWork W2256390272 @default.
- W1966787673 hasRelatedWork W2360664999 @default.
- W1966787673 hasRelatedWork W2811032335 @default.
- W1966787673 hasRelatedWork W3144495032 @default.
- W1966787673 hasRelatedWork W42051083 @default.
- W1966787673 hasVolume "73" @default.
- W1966787673 isParatext "false" @default.
- W1966787673 isRetracted "false" @default.
- W1966787673 magId "1966787673" @default.
- W1966787673 workType "article" @default.