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• W1966789610 startingPage "1503" @default.
• W1966789610 abstract "The localization of the integrin α 6 β 4 , a transmembrane adhesion molecule associated with hemidesmosomes, was studied in mouse junctional epithelium (JE) by the use of monoclonal antibodies in indirect immunofluorescence microscopy. The results showed that the integrin a 6 subunit was expressed throughout the JE and was localized to the cell membranes, including the aspects facing the internal and external basal laminae. The β 4 subunit had a more restricted distribution. It was expressed only in cells facing the internal and the external basal laminae and had a basally polarized distribution. In other parts of gingival epithelium, both integrin subunits were mainly expressed at the basal aspects of basal epithelial cells. The basement membrane components, type IV collagen and laminin, could be detected only in the external basal lamina and in other basement membranes of gingival epithelium. The results indicate that the a 6 β 4 integrin, expressed in mouse JE, has a role in mediating the attachment of the cells to the basement membranes facing the connective tissue and the tooth." @default.
• W1966789610 created "2016-06-24" @default.
• W1966789610 creator A5003212140 @default.
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• W1966789610 date "1992-08-01" @default.
• W1966789610 modified "2023-10-15" @default.
• W1966789610 title "Immunolocalization of Integrin α6β4 in Mouse Junctional Epithelium Suggests an Anchoring Function to both the Internal and the External Basal Lamina" @default.
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• W1966789610 doi "https://doi.org/10.1177/00220345920710080801" @default.
• W1966789610 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1380525" @default.
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