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• W1966832010 abstract "The objective of this study was to investigate the reproductive success (fertility and fecundity) of medaka (Oryzias latipes) exposed to 4-nonylphenol (4-NP) in water and the viability of their F(1) offspring. In addition, we measured the bioconcentration of 4-NP in eggs. After a 21-d exposure to 100microg/l 4-NP, medaka showed reduced egg production and fertility. Hepatic vitellogenin levels were increased significantly in males treated with 10, 50 and 100microg/l of 4-NP. In the F(1) generations, the hatchability and time to hatching of embryos in the 100microg/l treatment group were adversely affected, and 2-7microg 4-NP/g egg was found in spawned eggs (the bioconcentration factor: 30-100). These results indicate that (1) 4-NP adversely affected the reproduction (fecundity and fertility) of adult medaka, (2) 4-NP accumulated in eggs through maternal transfer and (3) these levels of 4-NP were associated with adverse effects in the F(1) offspring." @default.
• W1966832010 created "2016-06-24" @default.
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• W1966832010 date "2006-11-01" @default.
• W1966832010 modified "2023-10-16" @default.
• W1966832010 title "Reproductive effects and bioconcentration of 4-nonylphenol in medaka fish (Oryzias latipes)" @default.
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• W1966832010 doi "https://doi.org/10.1016/j.chemosphere.2006.03.034" @default.
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