FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966838097> ?p ?o ?g. }

• W1966838097 endingPage "159" @default.
• W1966838097 startingPage "155" @default.
• W1966838097 abstract "Correctly determined susceptibility breakpoints are important to both the individual patient and to society at large. A previously derived patient population pharmacokinetic model and Monte Carlo simulation (9999 patients) were used to create a likelihood distribution of tigecycline exposure, as measured by the area under the concentration–time curve at 24 h (AUC24). Each resultant AUC24 value was paired with a clinically relevant fixed MIC value ranging from 0.12 to 2 mg/L. For each AUC24–MIC pair, the probability of microbiologic response was calculated using an exposure–response relationship, which was derived from patients with complicated skin and skin structure infections that involved Staphylococcus aureus or streptococci or both. The median probability of microbiologic success was 94% or greater for MIC values up to and including 0.25 mg/L. The median probability of microbiologic success was 66% or less for MIC values of 0.5 mg/L or greater. These data support a susceptibility breakpoint of 0.25 mg/L for S. aureus and streptococci." @default.
• W1966838097 created "2016-06-24" @default.
• W1966838097 creator A5013759582 @default.
• W1966838097 creator A5032146892 @default.
• W1966838097 creator A5040884440 @default.
• W1966838097 creator A5043407893 @default.
• W1966838097 creator A5058850371 @default.
• W1966838097 creator A5060961800 @default.
• W1966838097 creator A5077814379 @default.
• W1966838097 date "2009-02-01" @default.
• W1966838097 modified "2023-09-23" @default.
• W1966838097 title "Application of patient population-derived pharmacokinetic–pharmacodynamic relationships to tigecycline breakpoint determination for staphylococci and streptococci" @default.
• W1966838097 cites W1967476131 @default.
• W1966838097 cites W1983076976 @default.
• W1966838097 cites W2021867174 @default.
• W1966838097 cites W2034302582 @default.
• W1966838097 cites W2052532688 @default.
• W1966838097 cites W2060675886 @default.
• W1966838097 cites W2100566343 @default.
• W1966838097 cites W2101273146 @default.
• W1966838097 cites W2112111953 @default.
• W1966838097 cites W2127308195 @default.
• W1966838097 cites W2143541324 @default.
• W1966838097 cites W2144516770 @default.
• W1966838097 cites W2147441308 @default.
• W1966838097 cites W2158568849 @default.
• W1966838097 cites W2162465279 @default.
• W1966838097 cites W2163694873 @default.
• W1966838097 cites W2167119990 @default.
• W1966838097 cites W2168849436 @default.
• W1966838097 doi "https://doi.org/10.1016/j.diagmicrobio.2008.10.011" @default.
• W1966838097 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19150707" @default.
• W1966838097 hasPublicationYear "2009" @default.
• W1966838097 type Work @default.
• W1966838097 sameAs 1966838097 @default.
• W1966838097 citedByCount "21" @default.
• W1966838097 countsByYear W19668380972012 @default.
• W1966838097 countsByYear W19668380972013 @default.
• W1966838097 countsByYear W19668380972014 @default.
• W1966838097 countsByYear W19668380972015 @default.
• W1966838097 countsByYear W19668380972016 @default.
• W1966838097 countsByYear W19668380972017 @default.
• W1966838097 crossrefType "journal-article" @default.
• W1966838097 hasAuthorship W1966838097A5013759582 @default.
• W1966838097 hasAuthorship W1966838097A5032146892 @default.
• W1966838097 hasAuthorship W1966838097A5040884440 @default.
• W1966838097 hasAuthorship W1966838097A5043407893 @default.
• W1966838097 hasAuthorship W1966838097A5058850371 @default.
• W1966838097 hasAuthorship W1966838097A5060961800 @default.
• W1966838097 hasAuthorship W1966838097A5077814379 @default.
• W1966838097 hasConcept C104317684 @default.
• W1966838097 hasConcept C111113717 @default.
• W1966838097 hasConcept C112705442 @default.
• W1966838097 hasConcept C126322002 @default.
• W1966838097 hasConcept C138626823 @default.
• W1966838097 hasConcept C206936463 @default.
• W1966838097 hasConcept C2775965595 @default.
• W1966838097 hasConcept C2777027569 @default.
• W1966838097 hasConcept C2779489039 @default.
• W1966838097 hasConcept C2908647359 @default.
• W1966838097 hasConcept C3019249092 @default.
• W1966838097 hasConcept C501593827 @default.
• W1966838097 hasConcept C523546767 @default.
• W1966838097 hasConcept C54355233 @default.
• W1966838097 hasConcept C71924100 @default.
• W1966838097 hasConcept C86803240 @default.
• W1966838097 hasConcept C89423630 @default.
• W1966838097 hasConcept C99454951 @default.
• W1966838097 hasConceptScore W1966838097C104317684 @default.
• W1966838097 hasConceptScore W1966838097C111113717 @default.
• W1966838097 hasConceptScore W1966838097C112705442 @default.
• W1966838097 hasConceptScore W1966838097C126322002 @default.
• W1966838097 hasConceptScore W1966838097C138626823 @default.
• W1966838097 hasConceptScore W1966838097C206936463 @default.
• W1966838097 hasConceptScore W1966838097C2775965595 @default.
• W1966838097 hasConceptScore W1966838097C2777027569 @default.
• W1966838097 hasConceptScore W1966838097C2779489039 @default.
• W1966838097 hasConceptScore W1966838097C2908647359 @default.
• W1966838097 hasConceptScore W1966838097C3019249092 @default.
• W1966838097 hasConceptScore W1966838097C501593827 @default.
• W1966838097 hasConceptScore W1966838097C523546767 @default.
• W1966838097 hasConceptScore W1966838097C54355233 @default.
• W1966838097 hasConceptScore W1966838097C71924100 @default.
• W1966838097 hasConceptScore W1966838097C86803240 @default.
• W1966838097 hasConceptScore W1966838097C89423630 @default.
• W1966838097 hasConceptScore W1966838097C99454951 @default.
• W1966838097 hasIssue "2" @default.
• W1966838097 hasLocation W19668380971 @default.
• W1966838097 hasLocation W19668380972 @default.
• W1966838097 hasOpenAccess W1966838097 @default.
• W1966838097 hasPrimaryLocation W19668380971 @default.
• W1966838097 hasRelatedWork W18383156 @default.
• W1966838097 hasRelatedWork W1966838097 @default.
• W1966838097 hasRelatedWork W2001555823 @default.
• W1966838097 hasRelatedWork W2013935350 @default.
• W1966838097 hasRelatedWork W2026176496 @default.
• W1966838097 hasRelatedWork W2326830576 @default.
• W1966838097 hasRelatedWork W2382345126 @default.

• next