Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966838997> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W1966838997 endingPage "1634" @default.
- W1966838997 startingPage "1631" @default.
- W1966838997 abstract "A 62-year-old Caucasian woman underwent evaluation for possible liver transplantation. She had end-stage cirrhosis secondary to hepatitis C and alcohol abuse. Among the tests ordered were urine screens for various drugs of abuse, including amphetamines, for which the patient's urine sample was positive. Given the patient's history of alcohol abuse and possible other drug abuse, her physicians questioned her in detail about recent use of any illicit substances. The patient stated emphatically that she had used no recreational drugs for the past 15 years. The physicians wondered what could be the cause of a false-positive result and relayed to the laboratory that the patient was on several medications. The laboratory arranged to have the initial sample analyzed for amphetamines by GC-MS. The result was reported as negative for amphetamine, methamphetamine, 3,4-methylenedioxy-methamphetamine (MDMA),3 and 3,4-methylenedioxy-amphetamine (MDA). In addition, the laboratory contacted the manufacturer of the screening immunoassay used [Amphetamines II, a kinetic interaction of microparticles in solution (KIMS) assay; Roche Diagnostics] and was informed that the medications that the patient had been prescribed, namely trazodone and bupropion, had been tested and did not exhibit any cross-reactivity.Amphetamines are a group of compounds that include amphetamine, methamphetamine, MDMA, and a large number of “designer drugs.” Widespread abuse has been reported worldwide and has increased over the last decade (1). In the clinical laboratory, the detection of amphetamine abuse has become increasingly important because of the potential for adverse drug–drug interactions involving existing prescription pharmaceuticals. Many antidepressants and antipsychotics function by affecting concentrations of dopamine, norepinephrine, and/or serotonin. Likewise, amphetamines increase concentrations of these biogenic amines by blocking their uptake by plasma membrane and/or vesicular transporters. Thus, in addition to their well-documented habit-forming properties and toxicities (2), amphetamines are of concern to clinicians because of their potentially toxic or fatal drug–drug interactions …" @default.
- W1966838997 created "2016-06-24" @default.
- W1966838997 creator A5003781893 @default.
- W1966838997 creator A5032952198 @default.
- W1966838997 creator A5051155730 @default.
- W1966838997 creator A5053931189 @default.
- W1966838997 creator A5079517489 @default.
- W1966838997 date "2012-12-01" @default.
- W1966838997 modified "2023-10-16" @default.
- W1966838997 title "Prescription Compliance or Illicit Designer Drug Abuse?" @default.
- W1966838997 cites W1964812356 @default.
- W1966838997 cites W2024371333 @default.
- W1966838997 cites W2033267911 @default.
- W1966838997 cites W2064756514 @default.
- W1966838997 cites W2067160581 @default.
- W1966838997 cites W2071612381 @default.
- W1966838997 cites W2114153737 @default.
- W1966838997 cites W2118074811 @default.
- W1966838997 cites W2415708495 @default.
- W1966838997 cites W4254175311 @default.
- W1966838997 doi "https://doi.org/10.1373/clinchem.2011.174649" @default.
- W1966838997 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23193148" @default.
- W1966838997 hasPublicationYear "2012" @default.
- W1966838997 type Work @default.
- W1966838997 sameAs 1966838997 @default.
- W1966838997 citedByCount "5" @default.
- W1966838997 countsByYear W19668389972015 @default.
- W1966838997 countsByYear W19668389972016 @default.
- W1966838997 countsByYear W19668389972019 @default.
- W1966838997 countsByYear W19668389972020 @default.
- W1966838997 countsByYear W19668389972021 @default.
- W1966838997 crossrefType "journal-article" @default.
- W1966838997 hasAuthorship W1966838997A5003781893 @default.
- W1966838997 hasAuthorship W1966838997A5032952198 @default.
- W1966838997 hasAuthorship W1966838997A5051155730 @default.
- W1966838997 hasAuthorship W1966838997A5053931189 @default.
- W1966838997 hasAuthorship W1966838997A5079517489 @default.
- W1966838997 hasBestOaLocation W19668389971 @default.
- W1966838997 hasConcept C118552586 @default.
- W1966838997 hasConcept C15744967 @default.
- W1966838997 hasConcept C2426938 @default.
- W1966838997 hasConcept C2780035454 @default.
- W1966838997 hasConcept C2781460075 @default.
- W1966838997 hasConcept C2911165735 @default.
- W1966838997 hasConcept C3018481051 @default.
- W1966838997 hasConcept C3020689752 @default.
- W1966838997 hasConcept C40010229 @default.
- W1966838997 hasConcept C545542383 @default.
- W1966838997 hasConcept C71924100 @default.
- W1966838997 hasConcept C77805123 @default.
- W1966838997 hasConcept C98274493 @default.
- W1966838997 hasConceptScore W1966838997C118552586 @default.
- W1966838997 hasConceptScore W1966838997C15744967 @default.
- W1966838997 hasConceptScore W1966838997C2426938 @default.
- W1966838997 hasConceptScore W1966838997C2780035454 @default.
- W1966838997 hasConceptScore W1966838997C2781460075 @default.
- W1966838997 hasConceptScore W1966838997C2911165735 @default.
- W1966838997 hasConceptScore W1966838997C3018481051 @default.
- W1966838997 hasConceptScore W1966838997C3020689752 @default.
- W1966838997 hasConceptScore W1966838997C40010229 @default.
- W1966838997 hasConceptScore W1966838997C545542383 @default.
- W1966838997 hasConceptScore W1966838997C71924100 @default.
- W1966838997 hasConceptScore W1966838997C77805123 @default.
- W1966838997 hasConceptScore W1966838997C98274493 @default.
- W1966838997 hasIssue "12" @default.
- W1966838997 hasLocation W19668389971 @default.
- W1966838997 hasLocation W19668389972 @default.
- W1966838997 hasOpenAccess W1966838997 @default.
- W1966838997 hasPrimaryLocation W19668389971 @default.
- W1966838997 hasRelatedWork W16807253 @default.
- W1966838997 hasRelatedWork W2033136441 @default.
- W1966838997 hasRelatedWork W2075657828 @default.
- W1966838997 hasRelatedWork W2187918721 @default.
- W1966838997 hasRelatedWork W2330748224 @default.
- W1966838997 hasRelatedWork W2399957492 @default.
- W1966838997 hasRelatedWork W2410217231 @default.
- W1966838997 hasRelatedWork W2901265344 @default.
- W1966838997 hasRelatedWork W2994402562 @default.
- W1966838997 hasRelatedWork W4287925734 @default.
- W1966838997 hasVolume "58" @default.
- W1966838997 isParatext "false" @default.
- W1966838997 isRetracted "false" @default.
- W1966838997 magId "1966838997" @default.
- W1966838997 workType "article" @default.