Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966852857> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W1966852857 abstract "Abstract The diagnosis of acute coronary syndrome (ACS) has challenged the minds of cardiologists, emergency physicians and laboratorists for decades. A major breakthrough has, however, occurred at the dawn of the third millennium, with development, commercialization and introduction into clinical practice of troponin immunoassays. A novel generation of these methods, conventionally defined as “high-sensitivity” (HS), has more recently emerged. These latest generation assays are characterized by improved analytical sensitivity, which would theoretically allow earlier and more efficient diagnosis of ACS. Despite the considerable amount of information gathered over the past few years about the clinical use of conventional and HS immunoassays, several doubts persist and – according to our personal perspective – the evidence that the latest generation methods would represent a real breakthrough in management of patients in short-stay units such as the emergency department is still an unresolved issue. Beside the mystifying nomenclature that characterizes several commercial tests, recent evidence suggests that the diagnostic performance of some contemporary sensitive methods would equal those of HS immunoassays for early diagnosis, serial assessment and even prognostication of patients. Conversely, the better diagnostic specificity of conventional methods may represent an advantage for triaging patients in overcrowded emergency departments. There is hence a tangible threat that the measurement of troponin with HS methods would become more or less an “expensive cholesterol of the third millennium”, and this risk must be carefully considered in a world of limited resources. So, our answer to the question if we do really need HS troponin immunoassays in the emergency department is “maybe not”." @default.
- W1966852857 created "2016-06-24" @default.
- W1966852857 creator A5073522064 @default.
- W1966852857 creator A5089475984 @default.
- W1966852857 date "2014-01-01" @default.
- W1966852857 modified "2023-10-14" @default.
- W1966852857 title "Do we really need high-sensitivity troponin immunoassays in the emergency department? Maybe not" @default.
- W1966852857 cites W1969142611 @default.
- W1966852857 cites W1971311823 @default.
- W1966852857 cites W2003517234 @default.
- W1966852857 cites W2043147357 @default.
- W1966852857 cites W2044459619 @default.
- W1966852857 cites W2064625391 @default.
- W1966852857 cites W2139243268 @default.
- W1966852857 cites W2151231511 @default.
- W1966852857 cites W2272962241 @default.
- W1966852857 doi "https://doi.org/10.1515/cclm-2013-0524" @default.
- W1966852857 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23898022" @default.
- W1966852857 hasPublicationYear "2014" @default.
- W1966852857 type Work @default.
- W1966852857 sameAs 1966852857 @default.
- W1966852857 citedByCount "11" @default.
- W1966852857 countsByYear W19668528572014 @default.
- W1966852857 countsByYear W19668528572015 @default.
- W1966852857 countsByYear W19668528572018 @default.
- W1966852857 countsByYear W19668528572019 @default.
- W1966852857 countsByYear W19668528572023 @default.
- W1966852857 crossrefType "journal-article" @default.
- W1966852857 hasAuthorship W1966852857A5073522064 @default.
- W1966852857 hasAuthorship W1966852857A5089475984 @default.
- W1966852857 hasConcept C118552586 @default.
- W1966852857 hasConcept C126322002 @default.
- W1966852857 hasConcept C177713679 @default.
- W1966852857 hasConcept C2777698277 @default.
- W1966852857 hasConcept C2780724011 @default.
- W1966852857 hasConcept C36036425 @default.
- W1966852857 hasConcept C500558357 @default.
- W1966852857 hasConcept C545542383 @default.
- W1966852857 hasConcept C71924100 @default.
- W1966852857 hasConceptScore W1966852857C118552586 @default.
- W1966852857 hasConceptScore W1966852857C126322002 @default.
- W1966852857 hasConceptScore W1966852857C177713679 @default.
- W1966852857 hasConceptScore W1966852857C2777698277 @default.
- W1966852857 hasConceptScore W1966852857C2780724011 @default.
- W1966852857 hasConceptScore W1966852857C36036425 @default.
- W1966852857 hasConceptScore W1966852857C500558357 @default.
- W1966852857 hasConceptScore W1966852857C545542383 @default.
- W1966852857 hasConceptScore W1966852857C71924100 @default.
- W1966852857 hasIssue "2" @default.
- W1966852857 hasLocation W19668528571 @default.
- W1966852857 hasLocation W19668528572 @default.
- W1966852857 hasOpenAccess W1966852857 @default.
- W1966852857 hasPrimaryLocation W19668528571 @default.
- W1966852857 hasRelatedWork W2124303977 @default.
- W1966852857 hasRelatedWork W2338206342 @default.
- W1966852857 hasRelatedWork W2366180072 @default.
- W1966852857 hasRelatedWork W2790973215 @default.
- W1966852857 hasRelatedWork W3008078763 @default.
- W1966852857 hasRelatedWork W3046938773 @default.
- W1966852857 hasRelatedWork W3094264331 @default.
- W1966852857 hasRelatedWork W3174697727 @default.
- W1966852857 hasRelatedWork W4283701958 @default.
- W1966852857 hasRelatedWork W4283757550 @default.
- W1966852857 hasVolume "52" @default.
- W1966852857 isParatext "false" @default.
- W1966852857 isRetracted "false" @default.
- W1966852857 magId "1966852857" @default.
- W1966852857 workType "article" @default.