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• W1966854087 abstract "Juvenile hormone (JH) titers must be modulated to permit the normal progress of development and reproduction in mosquitoes. In adult female Aedes aegypti, JH levels are low at adult eclosion, elevated in sugar-fed females and low again after a blood meal. Although degradation plays a role, JH titer is fundamentally determined by the rate of biosynthesis in the corpora allata gland (CA). CA from newly eclosed females (0-1 h after emergence) exhibit a very low basal JH biosynthetic activity, Aedes-allatotropin stimulates the CA in newly emerged females to produce JH. There is a correlation between nutritional reserves at adult emergence (teneral reserves) and CA activity. JH synthesis is significantly reduced in teneral females that emerge with low nutritional reserves. Taking a blood meal results in a reduction of CA activity. The biosynthetic activity of Ae. aegypti CA is significantly inhibited by factors present in the head, as well as by Anopheles gambiae PISCF-allatostatin. Nutritional signals affect the release of allatotropin and allatostatins by the brain resulting in the activation or inhibition of JH synthesis. JH is therefore an important part of a transduction mechanism that connects changes in the nutritional status with activation of specific physiological events during reproduction." @default.
• W1966854087 created "2016-06-24" @default.
• W1966854087 creator A5038969156 @default.
• W1966854087 date "2004-07-01" @default.
• W1966854087 modified "2023-09-30" @default.
• W1966854087 title "Nutritional regulation of JH synthesis: a mechanism to control reproductive maturation in mosquitoes?" @default.
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• W1966854087 doi "https://doi.org/10.1016/j.ibmb.2004.03.021" @default.
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