Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966867599> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W1966867599 endingPage "2219" @default.
- W1966867599 startingPage "2213" @default.
- W1966867599 abstract "We have analyzed the results of treatment of 117 patients with Ewing's sarcoma admitted to the National Cancer Institute since 1964. All patients received local irradiation to the primary site and a series of progressively more intensive systemic chemotherapy regimens using drugs known to be active as single agents in this disease. Four protocols were employed with varying numbers of patients in each treatment group. Initially, there appeared to be a difference among treatment groups with regard to disease-free survival (overall P =.06), with the later regimens having more favorable outcomes. We then undertook a statistical analysis of the influence of five pretreatment variables—age, sex, site of primary disease, serum lactic acid dehydrogenase (LDH), and metastatic status—on disease-free survival. Of these five factors, important indicators of favorable prognosis for the entire group (and for each of the treatment subgroups) were a distal site of primary disease, normal serum lactic acid dehydrogenase (LDH) level at presentation, and the absence of metastatic disease at the time of presentation. When we examined treatment results with respect to these prognostic factors, we found that the subgroups treated with the more aggressive regimens contained higher proportions of patients with favorable prognostic factors. After adjustment for differences in composition of treatment groups with respect to prognostic factors, the apparent difference in disease-free survival vanished (P =.62). These results indicate that in the case of Ewing's sarcoma, prognostic factors must be carefully considered in the design of treatment protocols and the subsequent analysis of end results." @default.
- W1966867599 created "2016-06-24" @default.
- W1966867599 creator A5002441488 @default.
- W1966867599 creator A5078394279 @default.
- W1966867599 creator A5081350762 @default.
- W1966867599 creator A5085429813 @default.
- W1966867599 creator A5086720552 @default.
- W1966867599 date "1980-04-15" @default.
- W1966867599 modified "2023-10-03" @default.
- W1966867599 title "Determination of prognostic factors and their influence on therapeutic results in patients with Ewing's sarcoma" @default.
- W1966867599 cites W1967390831 @default.
- W1966867599 cites W1973205433 @default.
- W1966867599 cites W1989378571 @default.
- W1966867599 cites W1992622163 @default.
- W1966867599 cites W2017678147 @default.
- W1966867599 cites W2027362334 @default.
- W1966867599 cites W2030785342 @default.
- W1966867599 cites W2041847119 @default.
- W1966867599 cites W2079708060 @default.
- W1966867599 cites W2109988968 @default.
- W1966867599 cites W2143594378 @default.
- W1966867599 cites W2165513037 @default.
- W1966867599 cites W2273559114 @default.
- W1966867599 cites W2414340841 @default.
- W1966867599 cites W4293241248 @default.
- W1966867599 doi "https://doi.org/10.1002/1097-0142(19800415)45:8<2213::aid-cncr2820450834>3.0.co;2-l" @default.
- W1966867599 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7370962" @default.
- W1966867599 hasPublicationYear "1980" @default.
- W1966867599 type Work @default.
- W1966867599 sameAs 1966867599 @default.
- W1966867599 citedByCount "87" @default.
- W1966867599 countsByYear W19668675992012 @default.
- W1966867599 countsByYear W19668675992013 @default.
- W1966867599 countsByYear W19668675992016 @default.
- W1966867599 countsByYear W19668675992021 @default.
- W1966867599 crossrefType "journal-article" @default.
- W1966867599 hasAuthorship W1966867599A5002441488 @default.
- W1966867599 hasAuthorship W1966867599A5078394279 @default.
- W1966867599 hasAuthorship W1966867599A5081350762 @default.
- W1966867599 hasAuthorship W1966867599A5085429813 @default.
- W1966867599 hasAuthorship W1966867599A5086720552 @default.
- W1966867599 hasBestOaLocation W19668675991 @default.
- W1966867599 hasConcept C121608353 @default.
- W1966867599 hasConcept C126322002 @default.
- W1966867599 hasConcept C141071460 @default.
- W1966867599 hasConcept C142724271 @default.
- W1966867599 hasConcept C143998085 @default.
- W1966867599 hasConcept C164465091 @default.
- W1966867599 hasConcept C2776694085 @default.
- W1966867599 hasConcept C2776907518 @default.
- W1966867599 hasConcept C2777586341 @default.
- W1966867599 hasConcept C2778162587 @default.
- W1966867599 hasConcept C2778256501 @default.
- W1966867599 hasConcept C2779134260 @default.
- W1966867599 hasConcept C2780192828 @default.
- W1966867599 hasConcept C71924100 @default.
- W1966867599 hasConcept C90924648 @default.
- W1966867599 hasConceptScore W1966867599C121608353 @default.
- W1966867599 hasConceptScore W1966867599C126322002 @default.
- W1966867599 hasConceptScore W1966867599C141071460 @default.
- W1966867599 hasConceptScore W1966867599C142724271 @default.
- W1966867599 hasConceptScore W1966867599C143998085 @default.
- W1966867599 hasConceptScore W1966867599C164465091 @default.
- W1966867599 hasConceptScore W1966867599C2776694085 @default.
- W1966867599 hasConceptScore W1966867599C2776907518 @default.
- W1966867599 hasConceptScore W1966867599C2777586341 @default.
- W1966867599 hasConceptScore W1966867599C2778162587 @default.
- W1966867599 hasConceptScore W1966867599C2778256501 @default.
- W1966867599 hasConceptScore W1966867599C2779134260 @default.
- W1966867599 hasConceptScore W1966867599C2780192828 @default.
- W1966867599 hasConceptScore W1966867599C71924100 @default.
- W1966867599 hasConceptScore W1966867599C90924648 @default.
- W1966867599 hasIssue "8" @default.
- W1966867599 hasLocation W19668675991 @default.
- W1966867599 hasLocation W19668675992 @default.
- W1966867599 hasOpenAccess W1966867599 @default.
- W1966867599 hasPrimaryLocation W19668675991 @default.
- W1966867599 hasRelatedWork W1966867599 @default.
- W1966867599 hasRelatedWork W2013021256 @default.
- W1966867599 hasRelatedWork W2041847119 @default.
- W1966867599 hasRelatedWork W2076418400 @default.
- W1966867599 hasRelatedWork W2091390760 @default.
- W1966867599 hasRelatedWork W2128266953 @default.
- W1966867599 hasRelatedWork W2405897898 @default.
- W1966867599 hasRelatedWork W2415511625 @default.
- W1966867599 hasRelatedWork W2416044440 @default.
- W1966867599 hasRelatedWork W2420845136 @default.
- W1966867599 hasVolume "45" @default.
- W1966867599 isParatext "false" @default.
- W1966867599 isRetracted "false" @default.
- W1966867599 magId "1966867599" @default.
- W1966867599 workType "article" @default.