Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966884927> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W1966884927 endingPage "1088" @default.
- W1966884927 startingPage "1083" @default.
- W1966884927 abstract "Background Little is known about the visual outcome of children affected by an optic pathway glioma (OPG). Procedures We evaluated the long-term visual outcome of 32 consecutive children affected by OPG without neurofibromatosis type-1 referred to the Pediatric Department of Padua University and managed according to standardized strategies. Results Eight children received chemotherapy, 10 radiotherapy, 7 both chemotherapy and radiotherapy, whereas 7 were untreated. At presentation, visual acuity (VA) was normal in 22 children (13 unilaterally and 9 bilaterally), and reduced in 10. At follow-up, VA had improved in 6 patients; it was stable in 8 and worse in 18. Visual field, assessed in 29 children, was normal in 9 and reduced in 20. The number of children with some grade of visual impairment increased from 7 to 10 during follow-up. Of the 17 children in whom the tumor became significantly smaller, VA improved in 6, was stable in 3, and worse in 8. Of the 6 children with improved VA, 5 received radiotherapy, and their papilla was normal or mildly pale. After a median follow-up of 6 years, 26 patients are alive with stable disease. Conclusions The visual prognosis of children with OPG is unsatisfactory. Older children treated with radiotherapy seem to have a better visual outcome than younger children. Severe optic pallor at diagnosis or during follow-up may be indicative of a negative prognosis. Pediatr Blood Cancer. 2010;55:1083–1088. © 2010 Wiley-Liss, Inc." @default.
- W1966884927 created "2016-06-24" @default.
- W1966884927 creator A5016581324 @default.
- W1966884927 creator A5019580614 @default.
- W1966884927 creator A5042455579 @default.
- W1966884927 creator A5058520879 @default.
- W1966884927 creator A5078516774 @default.
- W1966884927 creator A5086530967 @default.
- W1966884927 creator A5090805593 @default.
- W1966884927 date "2010-10-26" @default.
- W1966884927 modified "2023-10-18" @default.
- W1966884927 title "Optic pathway glioma: Long-term visual outcome in children without neurofibromatosis type-1" @default.
- W1966884927 cites W1983462444 @default.
- W1966884927 cites W1995607634 @default.
- W1966884927 cites W2009957442 @default.
- W1966884927 cites W2016318689 @default.
- W1966884927 cites W2021866546 @default.
- W1966884927 cites W2037538572 @default.
- W1966884927 cites W2045959624 @default.
- W1966884927 cites W2062432621 @default.
- W1966884927 cites W2110737893 @default.
- W1966884927 cites W2120667391 @default.
- W1966884927 cites W2121828378 @default.
- W1966884927 cites W2157618479 @default.
- W1966884927 doi "https://doi.org/10.1002/pbc.22748" @default.
- W1966884927 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20979170" @default.
- W1966884927 hasPublicationYear "2010" @default.
- W1966884927 type Work @default.
- W1966884927 sameAs 1966884927 @default.
- W1966884927 citedByCount "68" @default.
- W1966884927 countsByYear W19668849272012 @default.
- W1966884927 countsByYear W19668849272013 @default.
- W1966884927 countsByYear W19668849272014 @default.
- W1966884927 countsByYear W19668849272015 @default.
- W1966884927 countsByYear W19668849272016 @default.
- W1966884927 countsByYear W19668849272017 @default.
- W1966884927 countsByYear W19668849272018 @default.
- W1966884927 countsByYear W19668849272019 @default.
- W1966884927 countsByYear W19668849272020 @default.
- W1966884927 countsByYear W19668849272021 @default.
- W1966884927 countsByYear W19668849272022 @default.
- W1966884927 countsByYear W19668849272023 @default.
- W1966884927 crossrefType "journal-article" @default.
- W1966884927 hasAuthorship W1966884927A5016581324 @default.
- W1966884927 hasAuthorship W1966884927A5019580614 @default.
- W1966884927 hasAuthorship W1966884927A5042455579 @default.
- W1966884927 hasAuthorship W1966884927A5058520879 @default.
- W1966884927 hasAuthorship W1966884927A5078516774 @default.
- W1966884927 hasAuthorship W1966884927A5086530967 @default.
- W1966884927 hasAuthorship W1966884927A5090805593 @default.
- W1966884927 hasConcept C118487528 @default.
- W1966884927 hasConcept C118552586 @default.
- W1966884927 hasConcept C126838900 @default.
- W1966884927 hasConcept C141071460 @default.
- W1966884927 hasConcept C187212893 @default.
- W1966884927 hasConcept C2776058522 @default.
- W1966884927 hasConcept C2776694085 @default.
- W1966884927 hasConcept C2778124894 @default.
- W1966884927 hasConcept C2778257484 @default.
- W1966884927 hasConcept C2778984943 @default.
- W1966884927 hasConcept C2781372952 @default.
- W1966884927 hasConcept C509974204 @default.
- W1966884927 hasConcept C71924100 @default.
- W1966884927 hasConceptScore W1966884927C118487528 @default.
- W1966884927 hasConceptScore W1966884927C118552586 @default.
- W1966884927 hasConceptScore W1966884927C126838900 @default.
- W1966884927 hasConceptScore W1966884927C141071460 @default.
- W1966884927 hasConceptScore W1966884927C187212893 @default.
- W1966884927 hasConceptScore W1966884927C2776058522 @default.
- W1966884927 hasConceptScore W1966884927C2776694085 @default.
- W1966884927 hasConceptScore W1966884927C2778124894 @default.
- W1966884927 hasConceptScore W1966884927C2778257484 @default.
- W1966884927 hasConceptScore W1966884927C2778984943 @default.
- W1966884927 hasConceptScore W1966884927C2781372952 @default.
- W1966884927 hasConceptScore W1966884927C509974204 @default.
- W1966884927 hasConceptScore W1966884927C71924100 @default.
- W1966884927 hasIssue "6" @default.
- W1966884927 hasLocation W19668849271 @default.
- W1966884927 hasLocation W19668849272 @default.
- W1966884927 hasOpenAccess W1966884927 @default.
- W1966884927 hasPrimaryLocation W19668849271 @default.
- W1966884927 hasRelatedWork W2006349037 @default.
- W1966884927 hasRelatedWork W2060640572 @default.
- W1966884927 hasRelatedWork W2064171125 @default.
- W1966884927 hasRelatedWork W2154437048 @default.
- W1966884927 hasRelatedWork W2166316982 @default.
- W1966884927 hasRelatedWork W2964601176 @default.
- W1966884927 hasRelatedWork W2993308629 @default.
- W1966884927 hasRelatedWork W3118020789 @default.
- W1966884927 hasRelatedWork W4313455137 @default.
- W1966884927 hasRelatedWork W2419487063 @default.
- W1966884927 hasVolume "55" @default.
- W1966884927 isParatext "false" @default.
- W1966884927 isRetracted "false" @default.
- W1966884927 magId "1966884927" @default.
- W1966884927 workType "article" @default.