Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966941174> ?p ?o ?g. }
- W1966941174 endingPage "631" @default.
- W1966941174 startingPage "624" @default.
- W1966941174 abstract "Angiotensin-converting enzyme (ACE) inhibitors have been demonstrated to reduce morbidity and mortality rates in patients with heart failure with left ventricular systolic dysfunction. Nevertheless, these drugs are underutilized in current practice and prescribed at doses below those usually recommended. The aim of this work was to identify the social, demographic, laboratory, clinical, and therapeutic factors associated with nonprescription of ACE inhibitors and/or their prescription at doses below those recommended in the treatment of severe long-term congestive heart failure (CHF).An epidemiologic observational study, EPICAL (EPidémiologie de l'Insuffisance Cardiaque Avancée en Lorraine), studied 417 patients with severe CHF surviving after the index hospitalization. Multivariate logistic regression determined the factors associated with ACE inhibitor nonprescription and with their prescription at lower-than-recommended doses. ACE inhibitors were taken by 75% of the patients but 38% took lower-than-recommended doses. Factors shown to be associated with nonprescription included patients >65 years of age with renal impairment (odds ratio 19.5, confidence interval [CI] 7.9-48.0), nonsinus cardiac rhythm (odds ratio 2.0, CI 1.2-3.2), and prescription of potassium-sparing diuretics (odds ratio 2.4, CI 1. 2-4.7). Renal impairment was the single most important factor associated with prescription of lower-than-recommended doses, particularly in elderly patients.Our results underline the need for optimal and better use of ACE inhibitor therapy. CHF treatment guidelines must be more uniformly applied by all physicians caring for patients with heart failure." @default.
- W1966941174 created "2016-06-24" @default.
- W1966941174 creator A5007443163 @default.
- W1966941174 creator A5018071400 @default.
- W1966941174 creator A5022816161 @default.
- W1966941174 creator A5035588321 @default.
- W1966941174 creator A5036821495 @default.
- W1966941174 creator A5055004014 @default.
- W1966941174 creator A5055731738 @default.
- W1966941174 creator A5072408081 @default.
- W1966941174 date "2000-04-01" @default.
- W1966941174 modified "2023-10-17" @default.
- W1966941174 title "Determinants of angiotensin-converting enzyme inhibitor prescription in severe heart failure with left ventricular systolic dysfunction: The EPICAL study" @default.
- W1966941174 cites W1578335350 @default.
- W1966941174 cites W1606999574 @default.
- W1966941174 cites W1964369691 @default.
- W1966941174 cites W1970031019 @default.
- W1966941174 cites W1970824568 @default.
- W1966941174 cites W1981895083 @default.
- W1966941174 cites W1982093478 @default.
- W1966941174 cites W1994016751 @default.
- W1966941174 cites W1999218550 @default.
- W1966941174 cites W2007338020 @default.
- W1966941174 cites W2011761236 @default.
- W1966941174 cites W2017684000 @default.
- W1966941174 cites W2018666773 @default.
- W1966941174 cites W2029731065 @default.
- W1966941174 cites W2056861573 @default.
- W1966941174 cites W2060633147 @default.
- W1966941174 cites W2094884632 @default.
- W1966941174 cites W2095861713 @default.
- W1966941174 cites W2097640181 @default.
- W1966941174 cites W2104847567 @default.
- W1966941174 cites W2111234881 @default.
- W1966941174 cites W2120029068 @default.
- W1966941174 cites W2134743993 @default.
- W1966941174 cites W2136243194 @default.
- W1966941174 cites W2168317326 @default.
- W1966941174 cites W2220634303 @default.
- W1966941174 cites W2312388685 @default.
- W1966941174 cites W2323458614 @default.
- W1966941174 cites W2323549932 @default.
- W1966941174 cites W2326354230 @default.
- W1966941174 cites W2585382523 @default.
- W1966941174 cites W2769696378 @default.
- W1966941174 cites W3035983968 @default.
- W1966941174 cites W4210280888 @default.
- W1966941174 cites W4244073593 @default.
- W1966941174 cites W4245244523 @default.
- W1966941174 cites W4293085726 @default.
- W1966941174 cites W94388812 @default.
- W1966941174 doi "https://doi.org/10.1016/s0002-8703(00)90039-5" @default.
- W1966941174 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10740143" @default.
- W1966941174 hasPublicationYear "2000" @default.
- W1966941174 type Work @default.
- W1966941174 sameAs 1966941174 @default.
- W1966941174 citedByCount "58" @default.
- W1966941174 countsByYear W19669411742012 @default.
- W1966941174 countsByYear W19669411742015 @default.
- W1966941174 countsByYear W19669411742016 @default.
- W1966941174 countsByYear W19669411742017 @default.
- W1966941174 countsByYear W19669411742019 @default.
- W1966941174 countsByYear W19669411742021 @default.
- W1966941174 countsByYear W19669411742022 @default.
- W1966941174 countsByYear W19669411742023 @default.
- W1966941174 crossrefType "journal-article" @default.
- W1966941174 hasAuthorship W1966941174A5007443163 @default.
- W1966941174 hasAuthorship W1966941174A5018071400 @default.
- W1966941174 hasAuthorship W1966941174A5022816161 @default.
- W1966941174 hasAuthorship W1966941174A5035588321 @default.
- W1966941174 hasAuthorship W1966941174A5036821495 @default.
- W1966941174 hasAuthorship W1966941174A5055004014 @default.
- W1966941174 hasAuthorship W1966941174A5055731738 @default.
- W1966941174 hasAuthorship W1966941174A5072408081 @default.
- W1966941174 hasConcept C126322002 @default.
- W1966941174 hasConcept C151956035 @default.
- W1966941174 hasConcept C156957248 @default.
- W1966941174 hasConcept C164705383 @default.
- W1966941174 hasConcept C23131810 @default.
- W1966941174 hasConcept C2426938 @default.
- W1966941174 hasConcept C27016395 @default.
- W1966941174 hasConcept C2778198053 @default.
- W1966941174 hasConcept C2779611605 @default.
- W1966941174 hasConcept C44249647 @default.
- W1966941174 hasConcept C50440223 @default.
- W1966941174 hasConcept C71924100 @default.
- W1966941174 hasConcept C84393581 @default.
- W1966941174 hasConcept C98274493 @default.
- W1966941174 hasConceptScore W1966941174C126322002 @default.
- W1966941174 hasConceptScore W1966941174C151956035 @default.
- W1966941174 hasConceptScore W1966941174C156957248 @default.
- W1966941174 hasConceptScore W1966941174C164705383 @default.
- W1966941174 hasConceptScore W1966941174C23131810 @default.
- W1966941174 hasConceptScore W1966941174C2426938 @default.
- W1966941174 hasConceptScore W1966941174C27016395 @default.
- W1966941174 hasConceptScore W1966941174C2778198053 @default.
- W1966941174 hasConceptScore W1966941174C2779611605 @default.
- W1966941174 hasConceptScore W1966941174C44249647 @default.