FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966958324> ?p ?o ?g. }

• W1966958324 endingPage "159" @default.
• W1966958324 startingPage "151" @default.
• W1966958324 abstract "In this study, we sought to determine if prolactin (PRL) had any influence on burn-induced alterations in myelopoiesis and serum IL-6, IL-10, IL-12, IFN-gamma, TNF-alpha, and MCP-1 levels. To do this, we used mice that were PRL normal, PRL deficient, or hyperprolactinemic and had received a 15% total body surface area burn, sham treatment, or no treatment. We performed clonogenic assays of bone marrow cells, and we found that sham treatment significantly decreased monocyte/macrophage (M) colony formation relative to the control group in the PRL-deficient and PRL-normal mice (P < 0.01). Hyperprolactinemia attenuated the sham-induced decrease in M colony formation. Burn injury significantly increased M colony formation relative to the sham group with an equal significance in the PRL-deficient and PRL-normal mice (P < 0.05). We also showed that burn led to a significant increase in GM colony formation relative to the sham group. This burn-induced increase was significant in the PRL-normal (P < 0.05) and the PRL-deficient (P < 0.01) mice. In the PRL-normal mice, burn injury caused a 2.1-fold increase in the GM colony number, whereas in the PRL-deficient mice burn led to a 2.6-fold increase in GM colony number. When comparing the effects of burn injury on colony formation to the control groups, there were no significant differences seen, irrespective of the PRL level. We observed that all of the cytokines studied, with the exception of IL-10, were influenced by either sham treatment, burn injury, or both forms of stress. This stress-induced response occurred most often in animals that were either hypo- or hyperprolactinemic. We conclude that the PRL level was able to influence the sham-induced and burn-induced alterations in GM and M colony formation. Under euprolactinemic conditions, mice exhibited less often with stress-induced serum cytokine level alterations. We did not find any significant correlations with any of the serum cytokine levels and the ability to form colonies. Importantly, the sham treatment led to immune alterations independent of, and sometimes opposite of burn-induced effects." @default.
• W1966958324 created "2016-06-24" @default.
• W1966958324 creator A5035949192 @default.
• W1966958324 creator A5045280480 @default.
• W1966958324 creator A5047278434 @default.
• W1966958324 creator A5060379036 @default.
• W1966958324 creator A5062480352 @default.
• W1966958324 creator A5074739271 @default.
• W1966958324 creator A5087899903 @default.
• W1966958324 date "2004-02-01" @default.
• W1966958324 modified "2023-10-16" @default.
• W1966958324 title "Effects of Prolactin Level on Burn-Induced Aberrations in Myelopoiesis" @default.
• W1966958324 cites W1491638863 @default.
• W1966958324 cites W1592373661 @default.
• W1966958324 cites W1870986561 @default.
• W1966958324 cites W1973731890 @default.
• W1966958324 cites W1977341142 @default.
• W1966958324 cites W1988303474 @default.
• W1966958324 cites W1990882498 @default.
• W1966958324 cites W1994298028 @default.
• W1966958324 cites W1996047925 @default.
• W1966958324 cites W2000743809 @default.
• W1966958324 cites W2007864254 @default.
• W1966958324 cites W2012445733 @default.
• W1966958324 cites W2016888223 @default.
• W1966958324 cites W2020860419 @default.
• W1966958324 cites W2025028553 @default.
• W1966958324 cites W2037558223 @default.
• W1966958324 cites W2039612376 @default.
• W1966958324 cites W2041493456 @default.
• W1966958324 cites W2046627497 @default.
• W1966958324 cites W2054131916 @default.
• W1966958324 cites W2059145675 @default.
• W1966958324 cites W2073724618 @default.
• W1966958324 cites W2082522964 @default.
• W1966958324 cites W2091318921 @default.
• W1966958324 cites W2113844040 @default.
• W1966958324 cites W2119238166 @default.
• W1966958324 cites W2140957914 @default.
• W1966958324 cites W2146739323 @default.
• W1966958324 cites W2151113510 @default.
• W1966958324 cites W2313025629 @default.
• W1966958324 cites W2409312602 @default.
• W1966958324 cites W4237144135 @default.
• W1966958324 cites W4238927439 @default.
• W1966958324 cites W837474013 @default.
• W1966958324 cites W88613931 @default.
• W1966958324 doi "https://doi.org/10.1097/01.shk.0000108401.56565.e2" @default.
• W1966958324 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14752289" @default.
• W1966958324 hasPublicationYear "2004" @default.
• W1966958324 type Work @default.
• W1966958324 sameAs 1966958324 @default.
• W1966958324 citedByCount "13" @default.
• W1966958324 countsByYear W19669583242013 @default.
• W1966958324 countsByYear W19669583242016 @default.
• W1966958324 crossrefType "journal-article" @default.
• W1966958324 hasAuthorship W1966958324A5035949192 @default.
• W1966958324 hasAuthorship W1966958324A5045280480 @default.
• W1966958324 hasAuthorship W1966958324A5047278434 @default.
• W1966958324 hasAuthorship W1966958324A5060379036 @default.
• W1966958324 hasAuthorship W1966958324A5062480352 @default.
• W1966958324 hasAuthorship W1966958324A5074739271 @default.
• W1966958324 hasAuthorship W1966958324A5087899903 @default.
• W1966958324 hasBestOaLocation W19669583241 @default.
• W1966958324 hasConcept C109159458 @default.
• W1966958324 hasConcept C126322002 @default.
• W1966958324 hasConcept C134018914 @default.
• W1966958324 hasConcept C141071460 @default.
• W1966958324 hasConcept C17991360 @default.
• W1966958324 hasConcept C185592680 @default.
• W1966958324 hasConcept C2776782833 @default.
• W1966958324 hasConcept C2779064019 @default.
• W1966958324 hasConcept C2780007613 @default.
• W1966958324 hasConcept C28328180 @default.
• W1966958324 hasConcept C2993242423 @default.
• W1966958324 hasConcept C54355233 @default.
• W1966958324 hasConcept C71315377 @default.
• W1966958324 hasConcept C71924100 @default.
• W1966958324 hasConcept C86803240 @default.
• W1966958324 hasConcept C95862172 @default.
• W1966958324 hasConceptScore W1966958324C109159458 @default.
• W1966958324 hasConceptScore W1966958324C126322002 @default.
• W1966958324 hasConceptScore W1966958324C134018914 @default.
• W1966958324 hasConceptScore W1966958324C141071460 @default.
• W1966958324 hasConceptScore W1966958324C17991360 @default.
• W1966958324 hasConceptScore W1966958324C185592680 @default.
• W1966958324 hasConceptScore W1966958324C2776782833 @default.
• W1966958324 hasConceptScore W1966958324C2779064019 @default.
• W1966958324 hasConceptScore W1966958324C2780007613 @default.
• W1966958324 hasConceptScore W1966958324C28328180 @default.
• W1966958324 hasConceptScore W1966958324C2993242423 @default.
• W1966958324 hasConceptScore W1966958324C54355233 @default.
• W1966958324 hasConceptScore W1966958324C71315377 @default.
• W1966958324 hasConceptScore W1966958324C71924100 @default.
• W1966958324 hasConceptScore W1966958324C86803240 @default.
• W1966958324 hasConceptScore W1966958324C95862172 @default.
• W1966958324 hasIssue "2" @default.
• W1966958324 hasLocation W19669583241 @default.

• next