FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966971962> ?p ?o ?g. }

• W1966971962 endingPage "506" @default.
• W1966971962 startingPage "499" @default.
• W1966971962 abstract "Pulmonary hypertension (PH) is a chronic, complex, and progressive disease that eventuates in fatality. Research efforts over the past decades have resulted in therapeutic options that improve quality of life and prolong survival of patients, but they do not offer a cure. We propose a philosophical model that a disturbed balance of yin and yang results in pulmonary vascular remodeling, the hallmark of PH pathology. The model may be useful in exploring the wisdom of traditional Chinese medicine and incorporating it into mainstream PH research. In this context, the medicinal plant Rhodiola can be of profound interest owing to its variety of health‐friendly attributes. Rhodiola has been shown to be beneficial in high‐altitude‐related symptoms and acute exacerbation of PH; moreover, improvement of PH has been demonstrated experimentally in chronically hypoxic rats. The beneficial effects of Rhodiola in PH may be attributable to its potential targeting of the signaling pathways, such as endothelin‐1, nitric oxide, vascular endothelial growth factor, angiotensin‐converting enzyme, nuclear factor κ‐B, tumor necrosis factor α, and interleukin‐6. Alterations in these mediators are implicated in PH pathogenesis, the characteristics of which include chronic pulmonary vasoconstriction, vasoproliferation, and vascular inflammation. Salidroside, one of the compounds extracted from Rhodiola , has been found to provide therapeutic benefits in experimental PH. As the data are limited and the field is in its infancy, further studies including in‐depth analysis of the therapeutic effects on various animal models of PH are desirable. We believe that future PH research should place an adequate and special emphasis on exploring and promoting the potential of traditional Chinese medicine, and to this end, the medicinal plant Rhodiola offers a promising field on which to embark." @default.
• W1966971962 created "2016-06-24" @default.
• W1966971962 creator A5030300357 @default.
• W1966971962 creator A5036569097 @default.
• W1966971962 creator A5041650670 @default.
• W1966971962 creator A5043857150 @default.
• W1966971962 creator A5044426803 @default.
• W1966971962 creator A5047828152 @default.
• W1966971962 creator A5050016788 @default.
• W1966971962 creator A5055255847 @default.
• W1966971962 creator A5057524424 @default.
• W1966971962 date "2013-09-01" @default.
• W1966971962 modified "2023-10-18" @default.
• W1966971962 title "<i>Rhodiola</i>: An Ordinary Plant or a Promising Future Therapy for Pulmonary Hypertension? A Brief Review" @default.
• W1966971962 cites W1980391271 @default.
• W1966971962 cites W1986680797 @default.
• W1966971962 cites W1989862758 @default.
• W1966971962 cites W1992869528 @default.
• W1966971962 cites W1994283109 @default.
• W1966971962 cites W2003186313 @default.
• W1966971962 cites W2011477996 @default.
• W1966971962 cites W2014217144 @default.
• W1966971962 cites W2016512961 @default.
• W1966971962 cites W2019819067 @default.
• W1966971962 cites W2025593289 @default.
• W1966971962 cites W2050984607 @default.
• W1966971962 cites W2053366365 @default.
• W1966971962 cites W2062002285 @default.
• W1966971962 cites W2070328798 @default.
• W1966971962 cites W2075308691 @default.
• W1966971962 cites W2076831745 @default.
• W1966971962 cites W2079772033 @default.
• W1966971962 cites W2080848479 @default.
• W1966971962 cites W2084892030 @default.
• W1966971962 cites W2085559775 @default.
• W1966971962 cites W2117339256 @default.
• W1966971962 cites W2118844654 @default.
• W1966971962 cites W2142451713 @default.
• W1966971962 cites W2143248472 @default.
• W1966971962 cites W2145357984 @default.
• W1966971962 cites W2149499233 @default.
• W1966971962 cites W2159858352 @default.
• W1966971962 cites W2169220357 @default.
• W1966971962 cites W4293178741 @default.
• W1966971962 doi "https://doi.org/10.1086/674303" @default.
• W1966971962 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4070792" @default.
• W1966971962 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24618536" @default.
• W1966971962 hasPublicationYear "2013" @default.
• W1966971962 type Work @default.
• W1966971962 sameAs 1966971962 @default.
• W1966971962 citedByCount "25" @default.
• W1966971962 countsByYear W19669719622014 @default.
• W1966971962 countsByYear W19669719622016 @default.
• W1966971962 countsByYear W19669719622017 @default.
• W1966971962 countsByYear W19669719622018 @default.
• W1966971962 countsByYear W19669719622019 @default.
• W1966971962 countsByYear W19669719622020 @default.
• W1966971962 countsByYear W19669719622021 @default.
• W1966971962 countsByYear W19669719622022 @default.
• W1966971962 countsByYear W19669719622023 @default.
• W1966971962 crossrefType "journal-article" @default.
• W1966971962 hasAuthorship W1966971962A5030300357 @default.
• W1966971962 hasAuthorship W1966971962A5036569097 @default.
• W1966971962 hasAuthorship W1966971962A5041650670 @default.
• W1966971962 hasAuthorship W1966971962A5043857150 @default.
• W1966971962 hasAuthorship W1966971962A5044426803 @default.
• W1966971962 hasAuthorship W1966971962A5047828152 @default.
• W1966971962 hasAuthorship W1966971962A5050016788 @default.
• W1966971962 hasAuthorship W1966971962A5055255847 @default.
• W1966971962 hasAuthorship W1966971962A5057524424 @default.
• W1966971962 hasBestOaLocation W19669719621 @default.
• W1966971962 hasConcept C126322002 @default.
• W1966971962 hasConcept C151730666 @default.
• W1966971962 hasConcept C164027704 @default.
• W1966971962 hasConcept C177713679 @default.
• W1966971962 hasConcept C203014093 @default.
• W1966971962 hasConcept C2776914184 @default.
• W1966971962 hasConcept C2777439193 @default.
• W1966971962 hasConcept C2779343474 @default.
• W1966971962 hasConcept C2779526882 @default.
• W1966971962 hasConcept C2780505606 @default.
• W1966971962 hasConcept C2780930700 @default.
• W1966971962 hasConcept C60644358 @default.
• W1966971962 hasConcept C71924100 @default.
• W1966971962 hasConcept C86803240 @default.
• W1966971962 hasConcept C98274493 @default.
• W1966971962 hasConceptScore W1966971962C126322002 @default.
• W1966971962 hasConceptScore W1966971962C151730666 @default.
• W1966971962 hasConceptScore W1966971962C164027704 @default.
• W1966971962 hasConceptScore W1966971962C177713679 @default.
• W1966971962 hasConceptScore W1966971962C203014093 @default.
• W1966971962 hasConceptScore W1966971962C2776914184 @default.
• W1966971962 hasConceptScore W1966971962C2777439193 @default.
• W1966971962 hasConceptScore W1966971962C2779343474 @default.
• W1966971962 hasConceptScore W1966971962C2779526882 @default.
• W1966971962 hasConceptScore W1966971962C2780505606 @default.
• W1966971962 hasConceptScore W1966971962C2780930700 @default.
• W1966971962 hasConceptScore W1966971962C60644358 @default.

• next