FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966991812> ?p ?o ?g. }

• W1966991812 abstract "In the interferon (IFN) treatment of chronic hepatitis B, there is no accepted definition of virological response as measured by highly sensitive HBV DNA assays. In the present study of 98 patients given IFN (10 MU/day for 1 week, then 10 MU TIW for 11 weeks) with or without prednisolone priming, a virological response was identified as log HBV DNA/mL below 6.0 (by Amplicor Monitor, Roche) 6 months post-treatment. At this time, 92% (33/36) of the sustained responders (SR) still had detectable viraemia with log HBV DNA/mL at 4.30 +/- 0.15 (+/- SEM), as compared with 8.69 +/- 0.097 in nonsustained responders. Pretreatment viraemia below a threshold at 500 million copies/mL was associated with higher chance of response (P=0.023). Prednisolone enhanced the sustained response (53% vs. 30%, P=0.025), and in particular end-of-treatment response (ETR, 50% vs. 10%, P < 0.0001). ETR was predictive for SR (P < 0.0001), especially when log HBV DNA/mL was < 4.0 (PPV=92%). The potential value of differentiating the therapy of chronic hepatitis B on the basis of viraemia levels, as measured by highly sensitive assays, should be further investigated." @default.
• W1966991812 created "2016-06-24" @default.
• W1966991812 creator A5012020878 @default.
• W1966991812 creator A5039205319 @default.
• W1966991812 creator A5048497439 @default.
• W1966991812 creator A5078236677 @default.
• W1966991812 date "2001-09-01" @default.
• W1966991812 modified "2023-09-23" @default.
• W1966991812 title "Virological response to interferon therapy of chronic hepatitis B as measured by a highly sensitive assay" @default.
• W1966991812 cites W1589359966 @default.
• W1966991812 cites W1725758063 @default.
• W1966991812 cites W1800238637 @default.
• W1966991812 cites W1839180568 @default.
• W1966991812 cites W1940739348 @default.
• W1966991812 cites W1950099322 @default.
• W1966991812 cites W1969872269 @default.
• W1966991812 cites W1981456217 @default.
• W1966991812 cites W1983686289 @default.
• W1966991812 cites W1995269977 @default.
• W1966991812 cites W2015646660 @default.
• W1966991812 cites W2018479084 @default.
• W1966991812 cites W2021108107 @default.
• W1966991812 cites W2025566087 @default.
• W1966991812 cites W2032153894 @default.
• W1966991812 cites W2036327160 @default.
• W1966991812 cites W2041059721 @default.
• W1966991812 cites W2042653073 @default.
• W1966991812 cites W2043030289 @default.
• W1966991812 cites W2054071865 @default.
• W1966991812 cites W2055270948 @default.
• W1966991812 cites W2058793169 @default.
• W1966991812 cites W2060751492 @default.
• W1966991812 cites W2065640342 @default.
• W1966991812 cites W2065662036 @default.
• W1966991812 cites W2079535858 @default.
• W1966991812 cites W2082179562 @default.
• W1966991812 cites W2082256923 @default.
• W1966991812 cites W2088080811 @default.
• W1966991812 cites W2090041613 @default.
• W1966991812 cites W2091891213 @default.
• W1966991812 cites W2093391430 @default.
• W1966991812 cites W2098555404 @default.
• W1966991812 cites W2108308364 @default.
• W1966991812 cites W2122258488 @default.
• W1966991812 cites W2138930407 @default.
• W1966991812 cites W2140660147 @default.
• W1966991812 cites W2147406474 @default.
• W1966991812 cites W2149689743 @default.
• W1966991812 cites W2157468742 @default.
• W1966991812 cites W2159350572 @default.
• W1966991812 cites W2171896200 @default.
• W1966991812 cites W2319441763 @default.
• W1966991812 cites W2341203768 @default.
• W1966991812 cites W3152231134 @default.
• W1966991812 cites W4238592529 @default.
• W1966991812 cites W4246014144 @default.
• W1966991812 cites W4254366687 @default.
• W1966991812 cites W4362208329 @default.
• W1966991812 doi "https://doi.org/10.1046/j.1365-2893.2001.00306.x" @default.
• W1966991812 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11555192" @default.
• W1966991812 hasPublicationYear "2001" @default.
• W1966991812 type Work @default.
• W1966991812 sameAs 1966991812 @default.
• W1966991812 citedByCount "7" @default.
• W1966991812 crossrefType "journal-article" @default.
• W1966991812 hasAuthorship W1966991812A5012020878 @default.
• W1966991812 hasAuthorship W1966991812A5039205319 @default.
• W1966991812 hasAuthorship W1966991812A5048497439 @default.
• W1966991812 hasAuthorship W1966991812A5078236677 @default.
• W1966991812 hasConcept C126322002 @default.
• W1966991812 hasConcept C142462285 @default.
• W1966991812 hasConcept C159047783 @default.
• W1966991812 hasConcept C203014093 @default.
• W1966991812 hasConcept C2522874641 @default.
• W1966991812 hasConcept C2776178377 @default.
• W1966991812 hasConcept C2776185481 @default.
• W1966991812 hasConcept C2776715498 @default.
• W1966991812 hasConcept C3020491458 @default.
• W1966991812 hasConcept C71924100 @default.
• W1966991812 hasConcept C90924648 @default.
• W1966991812 hasConceptScore W1966991812C126322002 @default.
• W1966991812 hasConceptScore W1966991812C142462285 @default.
• W1966991812 hasConceptScore W1966991812C159047783 @default.
• W1966991812 hasConceptScore W1966991812C203014093 @default.
• W1966991812 hasConceptScore W1966991812C2522874641 @default.
• W1966991812 hasConceptScore W1966991812C2776178377 @default.
• W1966991812 hasConceptScore W1966991812C2776185481 @default.
• W1966991812 hasConceptScore W1966991812C2776715498 @default.
• W1966991812 hasConceptScore W1966991812C3020491458 @default.
• W1966991812 hasConceptScore W1966991812C71924100 @default.
• W1966991812 hasConceptScore W1966991812C90924648 @default.
• W1966991812 hasLocation W19669918121 @default.
• W1966991812 hasLocation W19669918122 @default.
• W1966991812 hasOpenAccess W1966991812 @default.
• W1966991812 hasPrimaryLocation W19669918121 @default.
• W1966991812 hasRelatedWork W1971078289 @default.
• W1966991812 hasRelatedWork W1986974467 @default.
• W1966991812 hasRelatedWork W1990238774 @default.
• W1966991812 hasRelatedWork W2029071048 @default.
• W1966991812 hasRelatedWork W2039086578 @default.

• next