FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1967017832> ?p ?o ?g. }

• W1967017832 endingPage "405" @default.
• W1967017832 startingPage "395" @default.
• W1967017832 abstract "The lateral nucleus of the amygdala (LA) is implicated in emotional and social behaviors. We recently showed that in horizontal brain slices, activation of NMDA receptors (NMDARs) is a requirement for persistent synaptic alterations in the LA, such as long-term potentiation (LTP) and long-term depression (LTD). In the LA, NR2A- and NR2B-type NMDRs coexist in synapses of LA projection neurons. We assessed the contribution of the two NMDAR subtypes to LA-LTP and LA-LTD in adult mouse brain slices by different induction protocols and by different inputs to LA neurons in the presence of different NMDAR subunit antagonists. In general, our results indicate that both NR2A and NR2B subunits are required for the formation of LA-LTP and LA-LTD. The abolishment or reduction of plasticity changes by these compounds could be due to the reduction in calcium influx via NMDARs. We also show, to our knowledge for the first time, that paired-pulse (40-msec interstimulus interval), low-frequency stimulation of external capsule fibers causes stable LTD. Rather than resulting from exclusive roles of the NMDAR subtypes, the synaptic plasticity response in the amygdala appears to be directed by the pattern of synaptic activation and the used inputs, which recruit the major NMDAR subtypes to variable extents." @default.
• W1967017832 created "2016-06-24" @default.
• W1967017832 creator A5001132073 @default.
• W1967017832 creator A5013869025 @default.
• W1967017832 creator A5041517451 @default.
• W1967017832 date "2009-05-27" @default.
• W1967017832 modified "2023-10-13" @default.
• W1967017832 title "Both NR2A and NR2B subunits of the NMDA receptor are critical for long-term potentiation and long-term depression in the lateral amygdala of horizontal slices of adult mice" @default.
• W1967017832 cites W1497791461 @default.
• W1967017832 cites W1543670539 @default.
• W1967017832 cites W1546002680 @default.
• W1967017832 cites W1589692855 @default.
• W1967017832 cites W1628708546 @default.
• W1967017832 cites W1703928766 @default.
• W1967017832 cites W1729062978 @default.
• W1967017832 cites W1803990964 @default.
• W1967017832 cites W1818033036 @default.
• W1967017832 cites W1876049211 @default.
• W1967017832 cites W1876061808 @default.
• W1967017832 cites W1965313832 @default.
• W1967017832 cites W1969914661 @default.
• W1967017832 cites W1972270334 @default.
• W1967017832 cites W1973436856 @default.
• W1967017832 cites W1976175452 @default.
• W1967017832 cites W1979231658 @default.
• W1967017832 cites W1980304996 @default.
• W1967017832 cites W1989440825 @default.
• W1967017832 cites W1990625157 @default.
• W1967017832 cites W1992875076 @default.
• W1967017832 cites W2001362807 @default.
• W1967017832 cites W2007178349 @default.
• W1967017832 cites W2008106418 @default.
• W1967017832 cites W2010957531 @default.
• W1967017832 cites W2014517835 @default.
• W1967017832 cites W2014520644 @default.
• W1967017832 cites W2014746087 @default.
• W1967017832 cites W2016379134 @default.
• W1967017832 cites W2017910024 @default.
• W1967017832 cites W2019196616 @default.
• W1967017832 cites W2020284109 @default.
• W1967017832 cites W2028558949 @default.
• W1967017832 cites W2028594041 @default.
• W1967017832 cites W2036543609 @default.
• W1967017832 cites W2038556607 @default.
• W1967017832 cites W2039156954 @default.
• W1967017832 cites W2039737543 @default.
• W1967017832 cites W2039789498 @default.
• W1967017832 cites W2040002918 @default.
• W1967017832 cites W2044818530 @default.
• W1967017832 cites W2044894106 @default.
• W1967017832 cites W2054387717 @default.
• W1967017832 cites W2059057631 @default.
• W1967017832 cites W2063897178 @default.
• W1967017832 cites W2064227979 @default.
• W1967017832 cites W2065169750 @default.
• W1967017832 cites W2068572983 @default.
• W1967017832 cites W2070037006 @default.
• W1967017832 cites W2071214963 @default.
• W1967017832 cites W2075665234 @default.
• W1967017832 cites W2077544438 @default.
• W1967017832 cites W2079302576 @default.
• W1967017832 cites W2081266275 @default.
• W1967017832 cites W2083883195 @default.
• W1967017832 cites W2085846947 @default.
• W1967017832 cites W2091598242 @default.
• W1967017832 cites W2095202445 @default.
• W1967017832 cites W2100193366 @default.
• W1967017832 cites W2100814580 @default.
• W1967017832 cites W2102591195 @default.
• W1967017832 cites W2104592186 @default.
• W1967017832 cites W2105857515 @default.
• W1967017832 cites W2108961156 @default.
• W1967017832 cites W2120048206 @default.
• W1967017832 cites W2120264644 @default.
• W1967017832 cites W2124366579 @default.
• W1967017832 cites W2136943552 @default.
• W1967017832 cites W2141984765 @default.
• W1967017832 cites W2143532600 @default.
• W1967017832 cites W2143742981 @default.
• W1967017832 cites W2145984134 @default.
• W1967017832 cites W2151425581 @default.
• W1967017832 cites W2154178019 @default.
• W1967017832 cites W2154836288 @default.
• W1967017832 cites W2157852654 @default.
• W1967017832 cites W2158553737 @default.
• W1967017832 cites W2160765931 @default.
• W1967017832 cites W2161998020 @default.
• W1967017832 cites W2164121465 @default.
• W1967017832 cites W2164644197 @default.
• W1967017832 cites W2169154493 @default.
• W1967017832 cites W2169458868 @default.
• W1967017832 cites W2340454904 @default.
• W1967017832 cites W4297846230 @default.
• W1967017832 doi "https://doi.org/10.1101/lm.1398709" @default.
• W1967017832 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19474217" @default.
• W1967017832 hasPublicationYear "2009" @default.
• W1967017832 type Work @default.
• W1967017832 sameAs 1967017832 @default.

• next