FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1967060250> ?p ?o ?g. }

• W1967060250 endingPage "2089" @default.
• W1967060250 startingPage "2083" @default.
• W1967060250 abstract "A monoclonal antibody (mAB 1C4C10) that reacts specifically with human nuclear proteins IEF 8Z30 and 8Z31 (charge variants; HeLa protein catalogue number; Bravo, R., and J. E. Celis, 1982, Clin. Chem., 28:766-781) has been microinjected into the cytoplasm of cultured cells that either express (primates) or lack these proteins (at least having similar molecular weights and pIs; other species), and its cellular localization has been determined by indirect immunofluorescence. Nuclear localization (nucleolar and nucleoplasmic) of the antibody was observed only in cells expressing these antigens, suggesting that a determinant present in IEF 8Z30 and 8Z31 is required for cytoplasm-nuclear translocation. Nuclear migration was not inhibited by cycloheximide, implying that these proteins may shuttle between nucleus and cytoplasm. The results assumed to support the signal rather than the free diffusion model are further supported by microinjection experiments using antibodies (proliferating cell nuclear antigen/cyclin, DNA) that react with nuclear components but do not recognize cytoplasmic antigens. Furthermore, they raise the possibility that some nonnuclear proteins may be transported to the nucleus by interacting with proteins harboring nuclear location signals." @default.
• W1967060250 created "2016-06-24" @default.
• W1967060250 creator A5007234546 @default.
• W1967060250 creator A5046195903 @default.
• W1967060250 creator A5087318688 @default.
• W1967060250 date "1986-12-01" @default.
• W1967060250 modified "2023-09-26" @default.
• W1967060250 title "Monoclonal antibody specific for human nuclear proteins IEF 8Z30 and 8Z31 accumulates in the nucleus a few hours after cytoplasmic microinjection of cells expressing these proteins." @default.
• W1967060250 cites W10743606 @default.
• W1967060250 cites W1522001100 @default.
• W1967060250 cites W1563742864 @default.
• W1967060250 cites W1805056380 @default.
• W1967060250 cites W1919026068 @default.
• W1967060250 cites W1965609818 @default.
• W1967060250 cites W1974012433 @default.
• W1967060250 cites W1989308870 @default.
• W1967060250 cites W1993028041 @default.
• W1967060250 cites W2007223204 @default.
• W1967060250 cites W2026137400 @default.
• W1967060250 cites W2027531387 @default.
• W1967060250 cites W2033722975 @default.
• W1967060250 cites W2042103412 @default.
• W1967060250 cites W2067829451 @default.
• W1967060250 cites W2069014796 @default.
• W1967060250 cites W2096787734 @default.
• W1967060250 cites W2099070975 @default.
• W1967060250 cites W2133531135 @default.
• W1967060250 cites W2147716555 @default.
• W1967060250 cites W2433097022 @default.
• W1967060250 cites W806105363 @default.
• W1967060250 doi "https://doi.org/10.1083/jcb.103.6.2083" @default.
• W1967060250 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2114576" @default.
• W1967060250 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3782292" @default.
• W1967060250 hasPublicationYear "1986" @default.
• W1967060250 type Work @default.
• W1967060250 sameAs 1967060250 @default.
• W1967060250 citedByCount "30" @default.
• W1967060250 countsByYear W19670602502019 @default.
• W1967060250 crossrefType "journal-article" @default.
• W1967060250 hasAuthorship W1967060250A5007234546 @default.
• W1967060250 hasAuthorship W1967060250A5046195903 @default.
• W1967060250 hasAuthorship W1967060250A5087318688 @default.
• W1967060250 hasBestOaLocation W19670602501 @default.
• W1967060250 hasConcept C104317684 @default.
• W1967060250 hasConcept C153911025 @default.
• W1967060250 hasConcept C159654299 @default.
• W1967060250 hasConcept C190062978 @default.
• W1967060250 hasConcept C2778236600 @default.
• W1967060250 hasConcept C2780114586 @default.
• W1967060250 hasConcept C2780723820 @default.
• W1967060250 hasConcept C29512474 @default.
• W1967060250 hasConcept C49805395 @default.
• W1967060250 hasConcept C54355233 @default.
• W1967060250 hasConcept C55493867 @default.
• W1967060250 hasConcept C59157529 @default.
• W1967060250 hasConcept C62525196 @default.
• W1967060250 hasConcept C86339819 @default.
• W1967060250 hasConcept C86803240 @default.
• W1967060250 hasConcept C94912109 @default.
• W1967060250 hasConcept C95444343 @default.
• W1967060250 hasConceptScore W1967060250C104317684 @default.
• W1967060250 hasConceptScore W1967060250C153911025 @default.
• W1967060250 hasConceptScore W1967060250C159654299 @default.
• W1967060250 hasConceptScore W1967060250C190062978 @default.
• W1967060250 hasConceptScore W1967060250C2778236600 @default.
• W1967060250 hasConceptScore W1967060250C2780114586 @default.
• W1967060250 hasConceptScore W1967060250C2780723820 @default.
• W1967060250 hasConceptScore W1967060250C29512474 @default.
• W1967060250 hasConceptScore W1967060250C49805395 @default.
• W1967060250 hasConceptScore W1967060250C54355233 @default.
• W1967060250 hasConceptScore W1967060250C55493867 @default.
• W1967060250 hasConceptScore W1967060250C59157529 @default.
• W1967060250 hasConceptScore W1967060250C62525196 @default.
• W1967060250 hasConceptScore W1967060250C86339819 @default.
• W1967060250 hasConceptScore W1967060250C86803240 @default.
• W1967060250 hasConceptScore W1967060250C94912109 @default.
• W1967060250 hasConceptScore W1967060250C95444343 @default.
• W1967060250 hasIssue "6" @default.
• W1967060250 hasLocation W19670602501 @default.
• W1967060250 hasLocation W19670602502 @default.
• W1967060250 hasLocation W19670602503 @default.
• W1967060250 hasLocation W19670602504 @default.
• W1967060250 hasOpenAccess W1967060250 @default.
• W1967060250 hasPrimaryLocation W19670602501 @default.
• W1967060250 hasRelatedWork W1967060250 @default.
• W1967060250 hasRelatedWork W1968930697 @default.
• W1967060250 hasRelatedWork W1990583149 @default.
• W1967060250 hasRelatedWork W1994669491 @default.
• W1967060250 hasRelatedWork W2041424868 @default.
• W1967060250 hasRelatedWork W2050225595 @default.
• W1967060250 hasRelatedWork W2070518772 @default.
• W1967060250 hasRelatedWork W2092656729 @default.
• W1967060250 hasRelatedWork W2309934042 @default.
• W1967060250 hasRelatedWork W2335345452 @default.
• W1967060250 hasVolume "103" @default.
• W1967060250 isParatext "false" @default.
• W1967060250 isRetracted "false" @default.
• W1967060250 magId "1967060250" @default.

• next