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- W1967075434 abstract "Abstract Facile access to the 2-substituted piperidine nucleus was achieved by a 3-component hetero Diels-Alder reaction. The use of an appropriately functionalized imine allowed the installation of a protecting group for both the piperidine and 2-position side chain nitrogens in one step. Also, by employing 2-trimethylsiloxy-1,3-butadiene, a reduction step was avoided, thus providing rapid entry into the piperidine core structure. This protocol led to the synthesis of some racemic 2-aminomethyl-4-oxo-piperidines; intermediates that were synthesized in multigram quantities." @default.
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- W1967075434 date "2003-01-06" @default.
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- W1967075434 title "A Facile Synthesis of Racemic 2-Aminomethyl-4-oxo-piperidine Intermediates" @default.
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- W1967075434 doi "https://doi.org/10.1081/scc-120018941" @default.
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