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• W1967098495 abstract "gem-Chloroamine CF3CH(Cl)NHAc 1 reacts in a one-pot sequence with NaN3 to afford trifluoromethyl azido compound 2 and further undergoes a Huisgen 1,3-dipolar cycloaddition with alkynes to yield 1,4-disubstitued 1,2,3-triazoles. The reaction is catalyzed by Cu(II) species (Cu(OAc)2, 10 mol %) without any reducing agent, and the corresponding products are afforded in high yields (74–87%). This process offers thus an entry to new trifluoromethyl pseudopeptides." @default.
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• W1967098495 date "2007-11-01" @default.
• W1967098495 modified "2023-10-04" @default.
• W1967098495 title "Synthesis of new trifluoromethyl peptidomimetics with a triazole moiety" @default.
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• W1967098495 doi "https://doi.org/10.1016/j.tetlet.2007.09.118" @default.
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