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- W1967133075 abstract "The consequence of direct exposure to HO. radical (chemically generated by Fenton's reaction) of partially purified rat liver PKC has been evaluated in this work. PKC inhibited Fenton-dependent HO. generation, probably due to the binding of copper ions to the enzyme. PKC activity was inhibited by H2O2. Copper ions were able to increase the H2O2-mediated damage to the enzyme, but only beyond a concentration threshold. The possible interactions between PKC and Fenton's reagents, in particular copper ions, is discussed." @default.
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- W1967133075 date "1996-10-01" @default.
- W1967133075 modified "2023-09-24" @default.
- W1967133075 title "Protein kinase C inactivation by Fenton's-reaction at discrete CU binding sites" @default.
- W1967133075 doi "https://doi.org/10.1080/15216549600201772" @default.
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