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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1967156632> ?p ?o ?g. }

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• W1967156632 abstract "Formaldehyde (FA), acetaldehyde (ACT), malondialdehyde (MDA) and acetone (ACON) were simultaneously identified in urine, and their excretion quantitated in response to chemically induced oxidative stress. Urine samples of female Sprague—Dawley rats were collected over dry ice and derivatized with 2,4-dinitrophenylhydrazine. The hydrazones of the four lipid metabolic products were quantitated by high-performance liquid chromatography on a Waters 10-μm μ-Bondapak C18 column. The identities of FA, ACT, MDA and ACON in urine were confirmed by gas chromatography—mass spectrometry. An oxidative stress was induced by orally administering 100 μg/kg 2,3,7,8-tetrachlorodibenzo-p-dioxin, 75 mg/kg paraquat, 6 mg/kg endrin or 2.5 ml/kg carbon tetrachloride to rats. Urinary excretion of FA, ACT, MDA and ACON increased relative to control animals 24 h after treatment with all xenobiotics. The system has wide-spread applicability to the investigation of altered lipid metabolism in disease states and exposure to environmental pollutants." @default.
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• W1967156632 date "1992-05-01" @default.
• W1967156632 modified "2023-10-07" @default.
• W1967156632 title "Excretion of formaldehyde, malondialdehyde, acetaldehyde and acetone in the urine of rats in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin, paraquat, endrin and carbon tetrachloride" @default.
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• W1967156632 doi "https://doi.org/10.1016/0378-4347(92)80196-w" @default.
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